Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.53 |
| ▸ | ADH1C | P00326 | 3/20 | 0.53 |
| ▸ | ADH1A | P07327 | 3/20 | 0.53 |
| ▸ | ADH4 | P08319 | 1/20 | 0.53 |
| ▸ | ADH7 | P40394 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 10/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28249045 | 0.79 | EPHX1 (0.59) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7135616 | 0.75 | EPHX1 (0.48) | EPHX1EPHX2NPC1RAB9ASMN1; SMN2 | |
| Cyclohexylformamide SCHEMBL28496813 | 0.73 | ADH1B (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL2109469 | 0.73 | ADH1B (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL9206597 | 0.73 | ADH1B (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL22988657 | 0.73 | ADH1B (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| Cyclohexylformamide SCHEMBL26146 | 0.73 | — | — | |
| SCHEMBL245391 | 0.73 | ADH1B (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL2112448 | 0.73 | ADH1B (1.00) | ADH1BADH1CADH1AADH4ADH7 | |
| SCHEMBL645299 | 0.73 | ADH1B (1.00) | ADH1BADH1CADH1AADH4ADH7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6506901-B2 | 1-(9H-Carbazol-4-yloxy)-3-((1-(7-trifluoromethyl-quinolin-4-yl) -piperidin-4-lmethyl)-amino)-propan-2-ol, for example; treating diabetes, urinary continence, atherosclerosis, gastrointestinal disorders, glaucoma | WYETH | 2003-01-14 | — | — | US | disclosed |
| US-20020037907-A1 | Substituted 2- (S) -hydroxy-3- (piperidin-4-yl-methylamino) -propyl ethers and substituted 2-aryl-2- (R) - hydroxy-1- (piperidin-4-yl-methyl) -ethylamine beta-3 adrenergic receptor agonists | AMERICAN HOME PRODUCTS CORPORATION (US) | 2002-03-28 | — | — | US | disclosed |
| WO-2002006255-A2 | HYDROXY-(PIPERIDIN-4-YL-METHYLAMINO)-ALKYL BETA-3 ADRENERGIC RECEPTOR ANTAGONISTS | WYETH (US) | 2002-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037907-A1 | Substituted 2- (S) -hydroxy-3- (piperidin-4-yl-methylamino) -propyl ethers and substituted 2-aryl-2- (R) - hydroxy-1- (piperidin-4-yl-methyl) -ethylamine beta-3 adrenergic receptor agonists | GPR119, ADRB1, ADRB2 | ADH1B 3463/4885ADH1C 230/4885ADH1A 661/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.