SCHEMBL7133262

SCHEMBL7133262

COC(C)OC=Cc1ccc(C=Cc2ccc(O)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
KDM4E B2RXH2 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
TTR P02766 3/20 0.47
CYP1A1 P04798 3/20 0.47
ALOX5 P09917 3/20 0.47
PTGS2 P35354 3/20 0.47
CYP1B1 Q16678 3/20 0.47
NPC1 O15118 2/20 0.47
ABL1 P00519 2/20 0.47
ABCB1 P08183 2/20 0.47
GAA P10253 2/20 0.47
BCR P11274 2/20 0.47
NQO2 P16083 2/20 0.47
PTGS1 P23219 2/20 0.47
RAB9A P51151 2/20 0.47
GFER P55789 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
MAPK1 P28482 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7645374 0.81 CA12 (0.44) MAPTKDM4EMEN1KMT2ATTR
SCHEMBL8093712 0.79 TRPA1 (0.44) CYP1A1CYP1B1NPC1MAPK1TP53
SCHEMBL6875173 0.76 STAT3 (0.37) MAPTKDM4EMEN1KMT2ATTR
SCHEMBL976834 0.74 APP (0.54) MAPTKDM4EMEN1KMT2ATTR
SCHEMBL10981021 0.74 APP (0.54) MAPTKDM4EMEN1KMT2ATTR
SCHEMBL6550911 0.74 APP (0.53) MAPTKDM4EMEN1KMT2ATTR
4-Hydroxybenzaldehyde SCHEMBL8727208 0.72 ALDH5A1 (0.64) MAPTKDM4EMEN1KMT2ATTR
Trans-4,4'-Dihydroxystilbene SCHEMBL145659 0.71 APP (0.74) MAPTKDM4EMEN1KMT2ATTR
Trans-4,4'-Dihydroxystilbene SCHEMBL491346 0.71 APP (0.74) MAPTKDM4EMEN1KMT2ATTR
SCHEMBL6266989 0.71 APP (0.74) MAPTKDM4EMEN1KMT2ATTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0780732-B1 Polymer composition and resist material WAKO PURE CHEM IND LTD (JP) 2003-07-09 EP disclosed
US-6303264-B1 PROFILE OF PATTERN OF QUARTER MICRON ORDER WITHOUT CAUSING FOOTING, WHILE RETAINING HIGH RESOLUTION ABILITY AND HIGH SENSITIVITY WAKO PURE CHEMICAL INDUSTRIES, LTD (JP) 2001-10-16 US disclosed
US-5976759-A ALKALI SOLUBLE BY HEATING WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1999-11-02 US disclosed
EP-0875787-A1 Method for reducing the substrate dependence of resist Wako Pure Chemical Industries, Ltd. (JP) 1998-11-04 EP disclosed
EP-0780732-A2 Polymer composition and resist material WAKO PURE CHEMICAL INDUSTRIES LTD (JP) 1997-06-25 EP disclosed