Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 8/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.41 |
| ▸ | LPAR1 | Q92633 | 3/20 | 0.41 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.41 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7722 | 0.90 | LPAR1 (0.48) | FFAR1LPAR1LPAR2LPAR3PPARD | |
| SCHEMBL7741 | 0.90 | CYP4F2 (0.39) | FFAR4LPAR1LPAR2LPAR3 | |
| SCHEMBL7136 | 0.88 | FFAR1 (0.43) | FFAR1FFAR4PPARD | |
| SCHEMBL6707 | 0.83 | LPAR1 (0.41) | LPAR1LPAR2LPAR3 | |
| SCHEMBL18597930 | 0.82 | PTGER1 (0.54) | FFAR1FFAR4LPAR1LPAR2LPAR3 | |
| SCHEMBL7260 | 0.82 | PTGER1 (0.50) | FFAR1FFAR4LPAR1LPAR2LPAR3 | |
| SCHEMBL1869 | 0.82 | LPAR1 (0.49) | LPAR1LPAR2LPAR3 | |
| SCHEMBL2265 | 0.82 | LPAR1 (0.49) | LPAR1LPAR2LPAR3 | |
| SCHEMBL6889 | 0.78 | FFAR1 (0.46) | FFAR1FFAR4LPAR1LPAR2LPAR3 | |
| SCHEMBL7576 | 0.78 | LPAR1 (0.44) | FFAR1FFAR4LPAR1LPAR2LPAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | claimed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | claimed |
| EP-2483252-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | Amira Pharmaceuticals, Inc. (US) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011041694-A2 | COMPOUNDS AS LYSOPHOSPHATIDIC ACID RECEPTOR ANTAGONISTS | AMIRA PHARMACEUTICALS, INC. (US) | 2011-04-07 | — | — | WO | disclosed |