Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL537593 | 0.81 | GGT1 (0.39) | ACLY | |
| SCHEMBL2638240 | 0.81 | GGT1 (0.39) | ACLY | |
| SCHEMBL6475315 | 0.81 | GGT1 (0.39) | ACLY | |
| SCHEMBL6989001 | 0.77 | MEN1 (0.45) | ACLY | |
| SCHEMBL6992300 | 0.77 | MEN1 (0.45) | ACLY | |
| SCHEMBL7134424 | 0.77 | ACLY (0.31) | ACLY | |
| SCHEMBL7134427 | 0.77 | ACLY (0.31) | ACLY | |
| SCHEMBL6988773 | 0.73 | ODC1 (0.42) | — | |
| SCHEMBL6987908 | 0.73 | NOS1 (0.33) | — | |
| SCHEMBL7140273 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317421-A1 | 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | Pharmacia Corporation (US) | 2003-06-11 | — | — | EP | claimed |
| WO-2002022562-A1 | 2-AMINO-2-ALKYL-5 HEPTENOIC AND HEPTYNOIC ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | PHARMACIA CORPORATION (US) | 2002-03-21 | — | — | WO | claimed |