Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 18/20 | 0.67 |
| ▸ | PARP15 | Q460N3 | 5/20 | 0.67 |
| ▸ | PARP4 | Q9UKK3 | 2/20 | 0.67 |
| ▸ | PARP14 | Q460N5 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | PARP16 | Q8N5Y8 | 1/20 | 0.67 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.67 |
| ▸ | PARP2 | Q9UGN5 | 4/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | PARP1 | P09874 | 1/20 | 0.61 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.52 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3137816 | 0.80 | PARP10 (1.00) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| Terephthalamide SCHEMBL538997 | 0.79 | PARP1 (0.63) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| Terephthalamide SCHEMBL15168441 | 0.79 | PARP1 (0.63) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| Terephthalamide SCHEMBL23774 | 0.79 | PARP1 (0.71) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL17226019 | 0.78 | PARP10 (0.70) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL6168637 | 0.78 | CA1 (0.60) | PARP10PARP15ALDH1A1KMT2ACA1 | |
| SCHEMBL23235849 | 0.76 | ST14 (0.67) | — | |
| SCHEMBL17888032 | 0.76 | PARP10 (0.67) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL15259341 | 0.76 | PARP10 (0.67) | PARP10PARP15PARP4PARP14ALDH1A1 | |
| SCHEMBL20369059 | 0.76 | PARP10 (0.67) | PARP10PARP15PARP4PARP14ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030092634-A1 | Novel compounds and compositions as protease inhibitors | AXYS PHARMACEUTICALS, INC. | 2003-05-15 | — | — | US | claimed |
| US-6506733-B1 | Which process comprises hydrogenating a compound of Formula 9: presence of a catalytic amount of 20% palladium hydroxide on carbon. | AXYS PHARMACEUTICALS, INC. | 2003-01-14 | — | — | US | claimed |
| EP-1159260-A1 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2001-12-05 | — | — | EP | claimed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | claimed |
| US-11944687-B2 | Carbohydrate conjugate RNA agents and process for their preparation | ALNYLAM PHARMACEUTICALS, INC. (US) | 2024-04-02 | — | — | US | disclosed |
| EP-4253395-A2 | PROCESSES FOR THE PREPARATION OF CARBOHYDRATE CONJUGATED RNA AGENTS | Alnylam Pharmaceuticals, Inc. (US) | 2023-10-04 | — | — | EP | disclosed |
| EP-2879718-B1 | PROCESSES FOR THE PREPARATION OF CARBOHYDRATE CONJUGATED RNA AGENTS | ALNYLAM PHARMACEUTICALS INC (US) | 2023-06-07 | — | — | EP | disclosed |
| US-20190134206-A1 | CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION | ALNYLAM PHARMACEUTICALS, INC. | 2019-05-09 | — | — | US | disclosed |
| US-10086081-B2 | Carbohydrate conjugated RNA agents and process for their preparation | ALNYLAM PHARMACEUTICALS, INC. (US) | 2018-10-02 | — | — | US | disclosed |
| US-20150196655-A1 | CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION | BANK OF AMERICA, N.A. | 2015-07-16 | — | — | US | disclosed |
| CN-104717982-A | Carbohydrate conjugates and improved process for their preparation | ALNYLAM PHARMACEUTICALS INC | 2015-06-17 | — | — | CN | disclosed |
| EP-2879718-A1 | CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION | Alnylam Pharmaceuticals, Inc. (US) | 2015-06-10 | — | — | EP | disclosed |
| WO-2000055124-A2 | NOVEL COMPOUNDS AND COMPOSITIONS AS PROTEASE INHIBITORS | AXYS PHARMACEUTICALS, INC. (US) | 2000-09-21 | — | — | WO | disclosed |
| EP-0014566-B1 | HALOGENATED BETA-LACTAM COMPOUNDS AND PROCESS FOR THEIR PREPARATION | ELI LILLY AND COMPANY (US) | 1983-05-25 | — | — | EP | disclosed |
| US-4357275-A | Novel oxazolinoazetidinones and process therefor | ELI LILLY AND COMPANY (US) | 1982-11-02 | — | — | US | disclosed |
| US-4271305-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| EP-0022628-A1 | Process for the preparation of oxazolinoazetidinones | ELI LILLY AND COMPANY (US) | 1981-01-21 | — | — | EP | disclosed |
| US-4243588-A | CYCLIZING A 2-CHLOROAZETIDINONE WITH LEAD FLUORIDE IN DIMETHYL SULFOXIDE TO OBTAIN THE 4-OXA-2,6-DIAZABICYCLO(3.2.0)HEPTANE | ELI LILLY AND COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4226986-A | 7-ACYLAMINO-3-HYDROXY-3-CEPHEM COMPOUND, TRIARYL PHOSPHITE DIHALIDE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0014566-A1 | Halogenated beta-lactam compounds and process for their preparation | ELI LILLY AND COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10086081-B2 | Carbohydrate conjugated RNA agents and process for their preparation | RNASE1, IGF2BP1, IGF2BP2 | PARP10 810/4885PARP15 1213/4885PARP4 866/4885 |
| US-20190134206-A1 | CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION | RNASE1, IGF2BP1, IGF2BP2 | PARP10 810/4885PARP15 1213/4885PARP4 866/4885 |
| US-20030092634-A1 | Novel compounds and compositions as protease inhibitors | SERPINB1, HPN, CTRL | PARP10 1469/4885PARP15 876/4885PARP4 1789/4885 |
| US-20150196655-A1 | CARBOHYDRATE CONJUGATED RNA AGENTS AND PROCESS FOR THEIR PREPARATION | RNASE1, IGF2BP1, IGF2BP2 | PARP10 810/4885PARP15 1213/4885PARP4 866/4885 |
| US-11944687-B2 | Carbohydrate conjugate RNA agents and process for their preparation | RNASE1, IGF2BP1, IGF2BP2 | PARP10 890/4885PARP15 1337/4885PARP4 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.