Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.44 |
| ▸ | ITK | Q08881 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6285577 | 0.99 | KMT2A (0.45) | KMT2APLK1ITKPOLBCTDSP1 | |
| SCHEMBL7148129 | 0.92 | RARB (0.47) | PLK1TRPV1THRBALDH1A1HTT | |
| Bromide SCHEMBL6282038 | 0.90 | RARB (0.46) | PLK1TRPV1THRBALDH1A1HTT | |
| SCHEMBL7143457 | 0.89 | THRA (0.50) | KMT2ATRPV1THRBALDH1A1MEN1 | |
| SCHEMBL7142545 | 0.88 | RAB9A (0.46) | KMT2APLK1ITKTRPV1ALDH1A1 | |
| Bromide SCHEMBL6276185 | 0.88 | THRA (0.49) | KMT2ATRPV1THRBALDH1A1MEN1 | |
| Bromide SCHEMBL6284151 | 0.87 | RAB9A (0.45) | KMT2APLK1ITKTRPV1ALDH1A1 | |
| SCHEMBL7147231 | 0.80 | ALDH1A1 (0.42) | KMT2AITKPOLBALDH1A1L3MBTL1 | |
| SCHEMBL7141616 | 0.78 | RAB9A (0.42) | KMT2AALDH1A1L3MBTL1HTTMEN1 | |
| Bromide SCHEMBL6282584 | 0.78 | ALDH1A1 (0.41) | KMT2AITKPOLBALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620825-B1 | 1,3-Azole compound substituted by pyridyl; administering as antiasthmatic, antiinflammatory or antiallergen agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| US-6436966-B1 | Adenosine A3 receptor antagonists | TAKEDA CHEMICAL IND., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |