Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 8/20 | 0.50 |
| ▸ | THRB | P10828 | 8/20 | 0.50 |
| ▸ | RARB | P10826 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | RARA | P10276 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6276185 | 0.99 | THRA (0.49) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL7148129 | 0.95 | RARB (0.47) | THRATHRBRARBALDH1A1MAPT | |
| Bromide SCHEMBL6282038 | 0.93 | RARB (0.46) | THRATHRBRARBALDH1A1MAPT | |
| SCHEMBL7140352 | 0.89 | KMT2A (0.46) | THRBMEN1KMT2AALDH1A1MAPT | |
| Bromide SCHEMBL6285577 | 0.88 | KMT2A (0.45) | THRBMEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7142545 | 0.83 | RAB9A (0.46) | KMT2AALDH1A1MAPTTRPV1 | |
| SCHEMBL7139170 | 0.77 | RARB (0.57) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL7147231 | 0.75 | ALDH1A1 (0.42) | KMT2AALDH1A1 | |
| SCHEMBL9667265 | 0.75 | THRA (0.61) | THRATHRBRARBMEN1KMT2A | |
| SCHEMBL9667141 | 0.75 | THRA (0.61) | THRATHRBRARBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620825-B1 | 1,3-Azole compound substituted by pyridyl; administering as antiasthmatic, antiinflammatory or antiallergen agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| US-6436966-B1 | Adenosine A3 receptor antagonists | TAKEDA CHEMICAL IND., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |