Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 3/20 | 0.47 |
| ▸ | PLK1 | P53350 | 1/20 | 0.47 |
| ▸ | THRA | P10827 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6282038 | 0.99 | RARB (0.46) | RARBPLK1THRATHRBTRPV1 | |
| SCHEMBL7143457 | 0.95 | THRA (0.50) | RARBTHRATHRBTRPV1ALDH1A1 | |
| Bromide SCHEMBL6276185 | 0.93 | THRA (0.49) | RARBTHRATHRBTRPV1ALDH1A1 | |
| SCHEMBL7140352 | 0.92 | KMT2A (0.46) | PLK1THRBTRPV1SMN1; SMN2LMNA | |
| Bromide SCHEMBL6285577 | 0.90 | KMT2A (0.45) | PLK1THRBTRPV1SMN1; SMN2LMNA | |
| SCHEMBL7142545 | 0.85 | RAB9A (0.46) | PLK1TRPV1SMN1; SMN2LMNAHTT | |
| Bromide SCHEMBL6284151 | 0.84 | RAB9A (0.45) | PLK1TRPV1SMN1; SMN2LMNAHTT | |
| SCHEMBL7147231 | 0.77 | ALDH1A1 (0.42) | SMN1; SMN2LMNAHTTALDH1A1HPGD | |
| SCHEMBL9641063 | 0.77 | RARB (0.56) | RARBPLK1THRATHRBTRPV1 | |
| Bromide SCHEMBL6282584 | 0.76 | ALDH1A1 (0.41) | SMN1; SMN2LMNAHTTALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620825-B1 | 1,3-Azole compound substituted by pyridyl; administering as antiasthmatic, antiinflammatory or antiallergen agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| US-6436966-B1 | Adenosine A3 receptor antagonists | TAKEDA CHEMICAL IND., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |