Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.41 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7148773 | 0.90 | AKR1C3 (0.44) | ALDH1A1MAPTKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL7140451 | 0.87 | MEN1 (0.46) | HPGDALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL215548 | 0.85 | PTGS2 (0.56) | HPGDALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL6092332 | 0.85 | PTGS2 (0.56) | HPGDALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL29527819 | 0.85 | PTGS2 (0.56) | HPGDALDH1A1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL7142073 | 0.85 | PTGS2 (0.41) | TSHRLMNAPTGS1PTGS2 | |
| SCHEMBL7148454 | 0.84 | PDK1 (0.45) | HPGDALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL7145053 | 0.84 | PTGS2 (0.42) | ALDH1A1LMNAPTGS1PTGS2 | |
| SCHEMBL7144308 | 0.83 | PTGS2 (0.43) | RAB9APTGS1PTGS2 | |
| SCHEMBL6094273 | 0.81 | PTGS2 (0.50) | HPGDALDH1A1MAPTKMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0977748-B1 | SUBSTITUTED BENZOPYRAN DERIVATIVES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2003-03-26 | — | — | EP | claimed |