SCHEMBL7141002

SCHEMBL7141002

O=C(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
CA2 P00918 13/20 0.37
LMNA P02545 1/20 0.35
CA1 P00915 12/20 0.34
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
GAA P10253 1/20 0.32
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL810923 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL811565 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810833 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL28450248 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL159453 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL428765 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10622506 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810417 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL3217875 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10617899 1.00 THRB (0.59) THRBCA2LMNACA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110616102-B Composite lubricating grease and preparation method thereof 武汉理工大学 2022-05-06 CN disclosed
CN-110616102-A Composite lubricating grease and preparation method thereof 武汉理工大学 2019-12-27 CN disclosed
US-6503873-B1 Shampooing hair or cleaning skin by applying N-acyl ethylenediaminetriacetic acid or salt HAMPSHIRE CHEMICAL CORP 2003-01-07 US disclosed
EP-0906393-A4 ULTRA MILD DETERGENT COMPOSITIONS HAMPSHIRE CHEMICAL CORP (US) 2000-10-25 EP disclosed
EP-0914411-A4 N-ACYL ETHYLENEDIAMINETRIACETIC ACID SURFACTANTS AS ENZYME COMPATIBLE SURFACTANTS, STABILIZERS AND ACTIVATORS HAMPSHIRE CHEMICAL CORP (US) 2000-06-07 EP disclosed
US-6057277-A AMYLASE AND LIPASE ENZYMES AND AS THE COMPATIBLE CHELATING SURFACTANT, SALTS OF N-ACYL ETHYLENEDIAMINETRIACETIC ACID WHICH ARE HIGHLY COMPATIBLE WITH SUCH ENZYMES TO INCREASE DETERGENT EFFECTIVENESS HAMPSHIRE CHEMICAL CORP. (US) 2000-05-02 US disclosed
EP-0914411-A1 N-ACYL ETHYLENEDIAMINETRIACETIC ACID SURFACTANTS AS ENZYME COMPATIBLE SURFACTANTS, STABILIZERS AND ACTIVATORS HAMPSHIRE CHEMICAL CORP. (US) 1999-05-12 EP disclosed
CN-1216572-A Very mild detergent compositions HAMPSHIRE CHEMICAL CORP (US) 1999-05-12 CN disclosed
CN-1216576-A N-acyl ethylenediaminetriacetic acid surfactants as enzyme compatible surfactants, stabilizers and activators HAMPSHIRE CHEMICAL CORP (US) 1999-05-12 CN disclosed
EP-0906393-A1 ULTRA MILD DETERGENT COMPOSITIONS HAMPSHIRE CHEMICAL CORPORATION (US) 1999-04-07 EP disclosed
EP-0629608-B1 Process for preparing N-acyl-N,N'N'-ethylenediaminetriacetic acid derivatives HAMPSHIRE CHEMICAL CORP (US) 1998-10-28 EP disclosed
US-5821215-A FOR USE IN DETERGENTS HAMPSHIRE CHEMICAL CORP. (US) 1998-10-13 US disclosed
EP-0861827-A2 N-acyl-n,n'n'-ethylenediaminetriacetic acid derivatives and process for preparing the same HAMPSHIRE CHEMICAL CORPORATION (US) 1998-09-02 EP disclosed
WO-1997040129-A1 N-ACYL ETHYLENEDIAMINETRIACETIC ACID SURFACTANTS AS ENZYME COMPATIBLE SURFACTANTS, STABILIZERS AND ACTIVATORS HAMPSHIRE CHEMICAL CORP. (US) 1997-10-30 WO disclosed
WO-1997040126-A1 ULTRA MILD DETERGENT COMPOSITIONS HAMPSHIRE CHEMICAL CORP. (US) 1997-10-30 WO disclosed
EP-0629608-A2 N-acyl-N,N'N'-ethylenediaminetriacetic acid derivatives and process for preparing same HAMPSHIRE CHEMICAL CORPORATION (US) 1994-12-21 EP disclosed
US-5284972-A N-acyl-N,N',N'-ethylenediaminetriacetic acid derivatives and process of preparing same HAMPSHIRE CHEMICAL CORP. (US) 1994-02-08 US disclosed