SCHEMBL810417

SCHEMBL810417

O=C(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
CA2 P00918 13/20 0.37
LMNA P02545 1/20 0.35
CA1 P00915 12/20 0.34
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
GAA P10253 1/20 0.32
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7141002 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810923 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL811565 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810833 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL28450248 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL159453 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL428765 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10622506 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL3217875 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10617899 1.00 THRB (0.59) THRBCA2LMNACA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117820584-A Modified amino resin and preparation method thereof 安徽省海徽化工有限公司 2024-04-05 CN claimed
CN-113336492-B Durable foam concrete and preparation method thereof 北京慕湖新材料技术有限公司 2021-11-26 CN claimed
CN-113336492-A Durable foam concrete and preparation method thereof 北京慕湖新材料技术有限公司 2021-09-03 CN claimed
CN-113355017-B Low-refractive-index optical fiber coating resin with high glass transition temperature 武汉长盈鑫科技有限公司 2022-04-29 CN disclosed
CN-113336492-B Durable foam concrete and preparation method thereof 北京慕湖新材料技术有限公司 2021-11-26 CN disclosed
CN-113355017-A Low-refractive-index optical fiber coating resin with high glass transition temperature 武汉长盈鑫科技有限公司 2021-09-07 CN disclosed
CN-113336492-A Durable foam concrete and preparation method thereof 北京慕湖新材料技术有限公司 2021-09-03 CN disclosed
EP-3464385-B1 PRODUCTION OF CHEMICALLY DERIVATIZED NANOCELLULOSE SAPPI NETHERLANDS SERVICES BV (NL) 2020-07-08 EP disclosed
EP-2389399-A2 FUNCTIONALIZED POLYURETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF Construction Research & Technology GmbH (DE) 2011-11-30 EP disclosed
US-20110256438-A1 WOUND-TYPE ACCUMULATOR JM ENERGY CORPORATION (JP) 2011-10-20 US disclosed
US-20100324205-A1 FLUID, FLUORINE-CONTAINING AND SINGLE-COMPONENT COMPOSITION CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2010-12-23 US disclosed
US-20090240004-A1 FUNCTIONALIZED POLYURETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2009-09-24 US disclosed
US-20090198000-A1 Liquid fluorine-containing and two-component compositions for the surface treatment of mineral and non-mineral substrates EVONIK DEGUSSA GMBH (DE) 2009-08-06 US disclosed
EP-2085442-A1 Compounds containing fluoride with improved surface characteristics Evonik Degussa GmbH (DE) 2009-08-05 EP disclosed
WO-2008040428-A2 FUNCTIONALIZED POLYURETHANE RESIN, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF CONSTRUCTION RESEARCH & TECHNOLOGY GMBH (DE) 2008-04-10 WO disclosed
US-7214819-B2 Fluorous triphasic reaction and separation processes for the generation of enantioenriched alcohols, amines, carboxylic acids and related compounds FLUOROUS TECHNOLOGIES, INC. (US) 2007-05-08 US disclosed
US-20040049071-A1 Fluorous triphasic reaction and separation processes for the generation of enantioenriched alcohols, amines, carboxylic acids and related compounds FLUOROUS TECHNOLOGIES, INC. 2004-03-11 US disclosed