SCHEMBL810833

SCHEMBL810833

O=C(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
CA2 P00918 13/20 0.37
LMNA P02545 1/20 0.35
CA1 P00915 12/20 0.34
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
GAA P10253 1/20 0.32
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7141002 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810923 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL811565 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL28450248 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL159453 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL428765 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10622506 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810417 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL3217875 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10617899 1.00 THRB (0.59) THRBCA2LMNACA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118161340-B Aqueous humor drainage tube 明澈生物科技(苏州)有限公司 2024-07-05 CN claimed
CN-118161340-A Aqueous humor drainage tube 明澈生物科技(苏州)有限公司 2024-06-11 CN claimed
US-11649202-B2 Fluorinated esters as lubricants for heat transfer fluids MEXICHEM FLUOR S.A. DE C.V. (MX) 2023-05-16 US claimed
CN-111499901-B Preparation method of fluorine-containing polymer/polyimide composite film 东莞东阳光科研发有限公司 2022-07-08 CN claimed
CN-111635546-B Preparation method of fluorine-containing polymer/polyimide composite film 东莞东阳光科研发有限公司 2022-04-29 CN claimed
CN-113336492-A Durable foam concrete and preparation method thereof 北京慕湖新材料技术有限公司 2021-09-03 CN claimed
CN-111635546-A Preparation method of fluorine-containing polymer/polyimide composite film 东莞东阳光科研发有限公司 2020-09-08 CN claimed
CN-111499901-A Preparation method of fluorine-containing polymer/polyimide composite film 东莞东阳光科研发有限公司 2020-08-07 CN claimed
EP-3529300-B1 PLASTICIZED PVC ADMIXTURES WITH SURFACE MODIFYING MACROMOLECULES AND ARTICLES MADE THEREFROM EVONIK CANADA INC (CA) 2026-05-06 EP disclosed
EP-3630212-B1 VASCULAR GRAFTS HAVING A MODIFIED SURFACE EVONIK CANADA INC (CA) 2026-02-11 EP disclosed
US-12540113-B2 Method of producing carboxylic acid fluoride KANTO DENKA KOGYO CO., LTD. (JP) 2026-02-03 US disclosed
US-12325788-B2 Plasticized PVC admixtures with surface modifying macromolecules and articles made therefrom Evonik Canada Inc. (CA) 2025-06-10 US disclosed
US-20250110101-A1 PER AND POLYFLUOROALKYL SUBSTANCE MEASUREMENT DEXSIL CORPORATION (US) 2025-04-03 US disclosed
CN-118978747-A Low-carbon high-barrier biodegradable mulch film and preparation method thereof 丹阳恒绿新材料有限公司 2024-11-19 CN disclosed
WO-1997040129-A1 N-ACYL ETHYLENEDIAMINETRIACETIC ACID SURFACTANTS AS ENZYME COMPATIBLE SURFACTANTS, STABILIZERS AND ACTIVATORS HAMPSHIRE CHEMICAL CORP. (US) 1997-10-30 WO disclosed
WO-1997040126-A1 ULTRA MILD DETERGENT COMPOSITIONS HAMPSHIRE CHEMICAL CORP. (US) 1997-10-30 WO disclosed
US-5284972-A N-acyl-N,N',N'-ethylenediaminetriacetic acid derivatives and process of preparing same HAMPSHIRE CHEMICAL CORP. (US) 1994-02-08 US disclosed
US-5162405-A Single-functional and mixtures of multi-functional oligomeric performance additive compositions and their uses ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-11-10 US disclosed
US-5013777-A Benzosulfonic acids as end groups of engineering thermoplastic resins; fireproofing; oxidation and UV resistances; photostabilizers ATOCHEM NORTH AMERICA, INC. (US) 1991-05-07 US disclosed
EP-0332761-A2 Single-functional and mixtures of multifunctional oligomeric performance additive compositions, and their use ELF ATOCHEM NORTH AMERICA, INC. (US) 1989-09-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11649202-B2 Fluorinated esters as lubricants for heat transfer fluids F12, MUC1, F13A1 THRB 3543/4885CA2 1038/4885LMNA 3139/4885
US-12540113-B2 Method of producing carboxylic acid fluoride CA3, CA6, CA1 THRB 578/4885CA2 5/4885LMNA 3105/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.