SCHEMBL3217875

SCHEMBL3217875

O=C(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
CA2 P00918 13/20 0.37
LMNA P02545 1/20 0.35
CA1 P00915 12/20 0.34
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
GAA P10253 1/20 0.32
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7141002 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810923 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL811565 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810833 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL28450248 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL159453 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL428765 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10622506 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810417 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10617899 1.00 THRB (0.59) THRBCA2LMNACA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240166658-A1 PORPHYRIN DERIVATIVES AND USES THEREOF UNIVERSITY OF TASMANIA (AU) 2024-05-23 US disclosed
EP-4298101-A1 PORPHYRIN DERIVATIVES AND USES THEREOF University Of Tasmania (AU) 2024-01-03 EP disclosed
WO-2022178593-A1 PORPHYRIN DERIVATIVES AND USES THEREOF UNIVERSITY OF TASMANIA (AU) 2022-09-01 WO disclosed
CN-113355017-B Low-refractive-index optical fiber coating resin with high glass transition temperature 武汉长盈鑫科技有限公司 2022-04-29 CN disclosed
CN-113355017-A Low-refractive-index optical fiber coating resin with high glass transition temperature 武汉长盈鑫科技有限公司 2021-09-07 CN disclosed
US-8436184-B2 6-(biphenyl-ester)-3H-naphtho[2,1-b]pyrans as photochromic dichroic dyes and optical article containing them ESSILOR INTERNATIONAL (COMPAGNIE GENERALE D'OPTIQUE (FR) 2013-05-07 US disclosed
US-20100039688-A1 6-(BIPHENYL-ESTER)-3H-NAPHTHO[2,1-B]PYRANS AS PHOTOCHROMIC DICHROIC DYES AND OPTICAL ARTICLE CONTAINING THEM ESSILOR INTERNATIONAL (FR) 2010-02-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100039688-A1 6-(BIPHENYL-ESTER)-3H-NAPHTHO[2,1-B]PYRANS AS PHOTOCHROMIC DICHROIC DYES AND OPTICAL ARTICLE CONTAINING THEM NR0B1, CBR1, NR0B2 THRB 723/4885CA2 982/4885LMNA 2174/4885
US-20240166658-A1 PORPHYRIN DERIVATIVES AND USES THEREOF PFAS, PCBP1, FGR THRB 889/4885CA2 2647/4885LMNA 4166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.