SCHEMBL159453

SCHEMBL159453

O=C(Cl)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.59
CA2 P00918 13/20 0.37
LMNA P02545 1/20 0.35
CA1 P00915 12/20 0.34
MMP1 P03956 2/20 0.34
MMP2 P08253 2/20 0.34
MMP9 P14780 2/20 0.34
MMP8 P22894 2/20 0.34
MMP13 P45452 2/20 0.34
GAA P10253 1/20 0.32
F2 P00734 1/20 0.31
PRSS1 P07477 1/20 0.31
PRSS2 P07478 1/20 0.31
PRSS3 P35030 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7141002 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810923 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL811565 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810833 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL28450248 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL428765 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10622506 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL810417 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL3217875 1.00 THRB (0.59) THRBCA2LMNACA1MMP1
SCHEMBL10617899 1.00 THRB (0.59) THRBCA2LMNACA1MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 632 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-121574332-A High-gloss water-based polyurethane and preparation method thereof 三晃树脂(佛山)有限公司 2026-02-27 CN claimed
US-20250230413-A1 METHODS AND SYSTEMS FOR THE CULTURE OF CELLS AT LIQUID-LIQUID INTERFACES UNIV LONDON QUEEN MARY (GB) 2025-07-17 US claimed
CN-120158200-A Polyester finishing paint for building curtain wall aluminum veneer 常州普利化工科技有限公司 2025-06-17 CN claimed
US-12332249-B1 Biomolecule detection method using diffusion ordered spectroscopy KUWAIT UNIVERSITY (KW) 2025-06-17 US claimed
CN-119913653-B Light and thin sweat-conducting quick-drying double-layer woven fabric with skin-core structure and preparation method and application thereof 广东洪兴实业股份有限公司 2025-06-10 CN claimed
CN-119529156-B Method for in-situ synthesis of perfluoroether rubber material by emulsion polymerization 上海熹贾精密技术有限公司 2025-05-27 CN claimed
CN-119432180-B Antibacterial anti-adhesion ceramic coating and preparation method thereof 江苏发银新材料有限公司 2025-05-23 CN claimed
CN-119913653-A Light and thin sweat-conducting quick-drying double-layer woven fabric with skin-core structure and preparation method and application thereof 广东洪兴实业股份有限公司 2025-05-02 CN claimed
CN-119859227-A Preparation method of polycarboxylate dispersant and application of polycarboxylate dispersant in pesticides 江苏东宝农化股份有限公司 2025-04-22 CN claimed
CN-119842291-A Super-stain-resistant water-based porcelain coating and preparation method thereof 陕西宝防建设工程有限公司 2025-04-18 CN claimed
CN-111268640-A Adaptive super-hydrophobic surface and preparation method thereof 电子科技大学 2020-06-12 CN claimed
CN-108047773-B Preparation method of sprayable transparent super-amphiphobic coating 成都高界科技有限公司 2020-02-04 CN claimed
CN-110656492-A High-performance oil-water separation material based on polyether-ether-ketone, preparation method and application thereof 吉林大学 2020-01-07 CN claimed
US-10335490-B2 Fluorinated polymerizable hydrogels for wound dressings and methods of making same THE UNIVERSITY OF AKRON 2019-07-02 US claimed
CN-109731526-A A kind of fluorine-containing surfactant compound and preparation method and application 中国石油大学(华东) 2019-05-10 CN claimed
US-7553911-B2 Coated polydivinylbenzene beads JORDI FLP (US) 2009-06-30 US claimed
US-20080255269-A1 Polystyrene divinylbenzene copolymer having a fluorinated, amidated surface; high performance liquid chromatography tationary phase JORDI HOWARD C 2008-10-16 US claimed
US-20010018512-A1 Chemical synthesis using solvent microdroplets UNIVERSITY OF WASHINGTON 2001-08-30 US claimed
EP-0970101-A2 SOLVENT FOR BIOPOLYMER SYNTHESIS, SOLVENT MICRODROPLETS AND METHODS OF USE UNIVERSITY OF WASHINGTON (US) 2000-01-12 EP claimed
WO-1998041531-A2 SOLVENT FOR BIOPOLYMER SYNTHESIS, SOLVENT MICRODROPLETS AND METHODS OF USE UNIVERSITY OF WASHINGTON (US) 1998-09-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10335490-B2 Fluorinated polymerizable hydrogels for wound dressings and methods of making same FLNB, FLNA, QSOX1 THRB 4586/4885CA2 1099/4885LMNA 4848/4885
US-20010018512-A1 Chemical synthesis using solvent microdroplets SUB1, MSN, SRM THRB 2612/4885CA2 1617/4885LMNA 1124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.