Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.42 |
| ▸ | ALDH3A1 | P30838 | 4/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | NOD1 | Q9Y239 | 4/20 | 0.39 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR7 | P34969 | 2/20 | 0.37 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
| ▸ | HTR1B | P28222 | 1/20 | 0.37 |
| ▸ | HTR1F | P30939 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5202769 | 0.86 | HTR6 (0.44) | HTR6ALDH3A1NOD1CXCL8TSHR | |
| SCHEMBL5201003 | 0.80 | NOD1 (0.57) | ALDH3A1NOD1CXCL8TSHRGAA | |
| SCHEMBL5204113 | 0.75 | TLR8 (0.43) | TSHRGAAALDH1A1TP53MAPK1 | |
| SCHEMBL28143695 | 0.73 | NR1H2 (0.51) | HTR6ALDH3A1NOD1CXCL8GAA | |
| SCHEMBL6423392 | 0.69 | HTR6 (0.50) | HTR6PLA2G2AHTR1AHTR7HTR1D | |
| SCHEMBL29808399 | 0.68 | ALDH3A1 (0.46) | HTR6ALDH3A1NOD1CXCL8GAA | |
| SCHEMBL5202583 | 0.65 | TP53 (0.39) | GAAALDH1A1TP53MAPK1HTT | |
| SCHEMBL14540341 | 0.64 | TLR8 (0.40) | GAAALDH1A1TP53MAPK1HTT | |
| SCHEMBL28144728 | 0.63 | NR1H2 (0.51) | HTR6ALDH3A1NOD1CXCL8GAA | |
| SCHEMBL28144740 | 0.63 | NR1H2 (0.51) | HTR6ALDH3A1NOD1CXCL8GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030191160-A1 | Substituted benzimidazoles as non-nucleoside inhibitors of reverse transcriptase | MICHEJDA CHRISTOPHER J (US) | 2003-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191160-A1 | Substituted benzimidazoles as non-nucleoside inhibitors of reverse transcriptase | SAMHD1, DUT, TYMP | HTR6 2269/4885ALDH3A1 417/4885PLA2G2A 4654/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.