SCHEMBL1055254

SCHEMBL1055254

Cc1ccccc1S(=O)(=O)O[Si](C)(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
ESR1 P03372 2/20 0.44
ESR2 Q92731 2/20 0.44
GAA P10253 1/20 0.44
POLB P06746 2/20 0.43
ALDH1A1 P00352 7/20 0.42
ATM Q13315 1/20 0.42
EDNRA P25101 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
HTR6 P50406 1/20 0.40
EDNRB P24530 1/20 0.40
TP53 P04637 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
KDM4E B2RXH2 1/20 0.38
RXFP1 Q9HBX9 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
HTT P42858 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31515627 0.79 KMT2A (0.49) KMT2AMEN1ESR1ESR2GAA
SCHEMBL9803 0.79 KMT2A (0.49) KMT2AMEN1ESR1ESR2GAA
SCHEMBL10793441 0.78 HSD11B1 (0.42) GAAEDNRACYP1A2CYP2C9CYP2C19
SCHEMBL8661206 0.77 ALDH1A1 (0.49) KMT2AGAAPOLBALDH1A1KDM4E
SCHEMBL260819 0.77 MEN1 (0.47) KMT2AMEN1ESR1ESR2GAA
SCHEMBL8019502 0.77 KMT2A (0.47) KMT2AMEN1ESR1ESR2GAA
SCHEMBL31244372 0.77 MEN1 (0.47) KMT2AMEN1ESR1ESR2GAA
SCHEMBL2187087 0.76 CA1 (0.52) KMT2AMEN1EDNRAHTR6EDNRB
SCHEMBL3396632 0.75 KMT2A (0.46) KMT2AMEN1ESR1ESR2GAA
SCHEMBL8984873 0.75 KMT2A (0.51) KMT2AMEN1ESR1ESR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025129550-A1 POLYORGANOSILOXANE COMPOSITION DOW SILICONES CORPORATION (US) 2025-06-26 WO claimed
US-20110220844-A1 SULFONATE MODIFIED NANOCRYSTALS Life Technologies Corporation 2011-09-15 US claimed
EP-2342161-A2 SULFONATE MODIFIED NANOCRYSTALS Life Technologies Corporation (US) 2011-07-13 EP claimed
WO-2010040111-A2 SULFONATE MODIFIED NANOCRYSTALS Life Technologies Corporation (US) 2010-04-08 WO claimed
WO-2025129550-A1 POLYORGANOSILOXANE COMPOSITION DOW SILICONES CORPORATION (US) 2025-06-26 WO disclosed
US-20250066621-A1 COMPOSITION FOR FILM FORMATION AND METHOD FOR MANUFACTURING SUBSTRATE CENTRAL GLASS COMPANY, LIMITED (JP) 2025-02-27 US disclosed
CN-119278504-A Substrate processing method and substrate manufacturing method 中央硝子株式会社 2025-01-07 CN disclosed
US-12163188-B2 Polymerase compositions and methods Life Technologies Corporation (US) 2024-12-10 US disclosed
WO-2024248021-A1 FILM-FORMING COMPOSITION, METHOD FOR PRODUCING SUBSTRATE, AND METHOD FOR PRODUCING FILM-FORMING COMPOSITION セントラル硝子株式会社 2024-12-05 WO disclosed
EP-4459666-A1 COMPOSITION FOR FILM FORMATION AND METHOD FOR PRODUCING SUBSTRATE Central Glass Company, Limited (JP) 2024-11-06 EP disclosed
WO-2024143097-A1 SUBSTRATE TREATING METHOD AND SUBSTRATE MANUFACTURING METHOD セントラル硝子株式会社 2024-07-04 WO disclosed
US-20230055565-A1 POLYMERASE COMPOSITIONS & METHODS Life Technologies Corporation (US) 2023-02-23 US disclosed
WO-2010111691-A2 CONJUGATES OF BIOMOLECULES TO NANOPARTICLES LIFE TECHNOLOGIES CORP (US) 2010-09-30 WO disclosed
WO-2010111690-A2 POLYMERASE COMPOSITIONS AND METHODS Life Technologies Corporation (US) 2010-09-30 WO disclosed
WO-2010111674-A2 METHODS AND APPARATUS FOR SINGLE MOLECULE SEQUENCING USING ENERGY TRANSFER DETECTION Life Technologies Corporation (US) 2010-09-30 WO disclosed
US-20100217020-A1 PROCESS FOR PRODUCING VITAMIN D DERIVATIVE USING CONVERGENT METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2010-08-26 US disclosed
WO-2010040111-A2 SULFONATE MODIFIED NANOCRYSTALS Life Technologies Corporation (US) 2010-04-08 WO disclosed
US-20090253905-A1 PROCESS FOR THE PREPARATION OF ONIUM SALTS WITH ALKYL- OR ARYLSULFONATE ANIONS OR ALKYL- OR ARYLCARBOXYLATE ANIONS HAVING A LOW HALIDE CONTENT MERCK PATENT GMBH (DE) 2009-10-08 US disclosed
EP-1955999-A1 METHOD FOR PRODUCING VITAMIN D DERIVATIVE BY USING CONVERGENT METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2008-08-13 EP disclosed
US-4565883-A Cyanoacrylate adhesive composition TEROSON GMBH (DE) 1986-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100217020-A1 PROCESS FOR PRODUCING VITAMIN D DERIVATIVE USING CONVERGENT METHOD CYP2R1, CYP24A1, VDR KMT2A 2928/4885MEN1 2805/4885ESR1 3553/4885
US-20090253905-A1 PROCESS FOR THE PREPARATION OF ONIUM SALTS WITH ALKYL- OR ARYLSULFONATE ANIONS OR ALKYL- OR ARYLCARBOXYLATE ANIONS HAVING A LOW HALIDE CONTENT ARSA, STS, SCLY KMT2A 2870/4885MEN1 4228/4885ESR1 2694/4885
US-12163188-B2 Polymerase compositions and methods POLN, POLI, POLRMT KMT2A 2735/4885MEN1 4479/4885ESR1 3418/4885
US-20230055565-A1 POLYMERASE COMPOSITIONS & METHODS POLN, POLI, POLRMT KMT2A 2450/4885MEN1 4477/4885ESR1 3612/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.