Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | AHR | P35869 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7150847 | 0.87 | NFE2L2 (0.39) | NFE2L2L3MBTL1KDM4EKMT2AMAPT | |
| SCHEMBL7097655 | 0.82 | NFE2L2 (0.44) | NFE2L2L3MBTL1GAAALDH1A1LMNA | |
| SCHEMBL6182309 | 0.73 | CYP1A2 (0.53) | L3MBTL1GAAALDH1A1LMNAKDM4E | |
| SCHEMBL10954259 | 0.71 | NFE2L2 (0.43) | NFE2L2L3MBTL1GAAALDH1A1LMNA | |
| SCHEMBL9953802 | 0.70 | SLC10A1 (0.34) | L3MBTL1ALDH1A1LMNAKDM4EMAPK1 | |
| SCHEMBL7094473 | 0.69 | NFE2L2 (0.43) | NFE2L2L3MBTL1ALDH1A1KMT2AMEN1 | |
| SCHEMBL8025197 | 0.67 | AOC3 (0.43) | L3MBTL1GAAALDH1A1LMNAMAPK1 | |
| SCHEMBL28708881 | 0.67 | ALDH1A1 (0.44) | L3MBTL1ALDH1A1LMNAMAPK1KMT2A | |
| SCHEMBL7506748 | 0.67 | GRM5 (0.42) | ALDH1A1KDM4EMAPK1KMT2ATSHR | |
| SCHEMBL9799547 | 0.64 | ALDH1A1 (0.47) | L3MBTL1GAAALDH1A1LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1341788-A2 | PYRAZOLOPYRIDINES | GLAXO GROUP LIMITED (GB) | 2003-09-10 | — | — | EP | disclosed |
| WO-2002048147-A2 | PYRAZOLOPYRIDINES | GLAXO GROUP LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |