Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8510243 | 0.85 | KCNA5 (0.32) | PDE4DPDE4APDE4BPDE4CPRMT5 | |
| SCHEMBL8510312 | 0.85 | KCNA5 (0.34) | LMNATAAR1 | |
| SCHEMBL28340566 | 0.84 | CTSL (0.44) | PDE4DPDE4APDE4BPDE4CLMNA | |
| SCHEMBL28340358 | 0.84 | CTSL (0.44) | PDE4DPDE4APDE4BPDE4CLMNA | |
| SCHEMBL11190973 | 0.84 | CTSL (0.44) | PDE4DPDE4APDE4BPDE4CLMNA | |
| SCHEMBL7458158 | 0.81 | OPRM1 (0.46) | MEN1KMT2AOPRM1TAAR1OPRK1 | |
| SCHEMBL10719153 | 0.81 | LTA4H (0.48) | KMT2A | |
| SCHEMBL10654667 | 0.80 | PRMT5 (0.33) | MEN1KMT2APDE4DPDE4APDE4B | |
| SCHEMBL29773826 | 0.80 | CTSL (0.37) | MEN1KMT2APDE4DLMNAMAPK1 | |
| SCHEMBL7455241 | 0.80 | TAAR1 (0.46) | LMNAOPRM1TAAR1OPRK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0966464-B1 | SUBSTITUTED 2,4-DIAMINOPYRIMIDINES | BASILEA PHARMACEUTICA AG (CH) | 2003-05-28 | — | — | EP | disclosed |
| US-6114330-A | BACTERICIDES | HOFFMANN-LA ROCHE INC. (US) | 2000-09-05 | — | — | US | disclosed |