Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 17/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.45 |
| ▸ | PPARG | P37231 | 5/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215582 | 0.83 | EPHX2 (0.57) | EPHX2ROCK2PPARGROCK1 | |
| SCHEMBL30353792 | 0.78 | EPHX2 (0.56) | EPHX2ROCK2ALOX5PPARGROCK1 | |
| SCHEMBL24077903 | 0.78 | EPHX2 (0.56) | EPHX2ROCK2ALOX5PPARGROCK1 | |
| SCHEMBL6258412 | 0.76 | ROCK2 (0.55) | EPHX2ROCK2ROCK1 | |
| SCHEMBL7142998 | 0.75 | MEN1 (0.43) | EPHX2PPARG | |
| SCHEMBL6253466 | 0.74 | MLYCD (0.49) | — | |
| SCHEMBL6254037 | 0.73 | MLYCD (0.52) | ROCK2ROCK1 | |
| SCHEMBL7093597 | 0.71 | ALDH1A1 (0.52) | ROCK2PPARG | |
| SCHEMBL5209564 | 0.70 | EPHX2 (0.57) | EPHX2ROCK2ALOX5PPARGROCK1 | |
| SCHEMBL5643051 | 0.70 | EPHX2 (0.79) | EPHX2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |