Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 5/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.39 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.39 |
| ▸ | NNMT | P40261 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211695 | 0.83 | MEN1 (0.52) | MEN1KMT2AGSK3BKLKB1MET | |
| SCHEMBL7093597 | 0.75 | ALDH1A1 (0.52) | MAOBPPARG | |
| SCHEMBL7143030 | 0.75 | EPHX2 (0.46) | PPARGEPHX2 | |
| SCHEMBL6258412 | 0.74 | ROCK2 (0.55) | MAOBEPHX2 | |
| SCHEMBL7141277 | 0.71 | ALK (0.42) | MEN1KMT2APPARG | |
| SCHEMBL5213150 | 0.70 | HPGD (0.57) | — | |
| SCHEMBL6253466 | 0.70 | MLYCD (0.49) | MAOB | |
| SCHEMBL13450242 | 0.69 | EPHX2 (0.62) | MEN1KMT2AGSK3BKLKB1MET | |
| SCHEMBL3460904 | 0.68 | EPHX2 (0.57) | MEN1KMT2AMAOBPPARGEPHX2 | |
| SCHEMBL6255361 | 0.68 | WDR5 (0.48) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362033-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | Warner-Lambert Company LLC (US) | 2003-11-19 | — | — | EP | claimed |
| WO-2002064568-A1 | PYRIDINE MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2002-08-22 | — | — | WO | claimed |