Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 3/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.37 |
| ▸ | PRKG1 | Q13976 | 4/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7099768 | 0.88 | L3MBTL1 (0.46) | HTR1ASLC6A4L3MBTL1CHRNA7KMT2A | |
| SCHEMBL7151596 | 0.83 | KDM4E (0.44) | KDM4ENPC1RAB9AL3MBTL1HTT | |
| SCHEMBL18618470 | 0.79 | ALDH1A1 (0.48) | KDM4EHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL25168119 | 0.77 | DPP4 (0.37) | KDM4EL3MBTL1 | |
| SCHEMBL7146974 | 0.76 | HTR1A (0.39) | HTR1ASLC6A4 | |
| SCHEMBL5756452 | 0.75 | CHRNA7 (0.39) | KDM4ENPC1RAB9AL3MBTL1DYRK1A | |
| SCHEMBL24164065 | 0.73 | GPR119 (0.37) | KDM4ENPC1RAB9AL3MBTL1ALDH1A1 | |
| SCHEMBL7099217 | 0.73 | GPR119 (0.51) | KDM4EL3MBTL1MEN1KMT2AEPHX2 | |
| Water SCHEMBL8023337 | 0.72 | DYRK1A (0.41) | HTR1AKDM4EDYRK1ACHRNA7HTT | |
| SCHEMBL23868538 | 0.71 | ROCK2 (0.50) | ROCK2PRKG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153764-A1 | Process for preparing 4-substituted piperidines | ELI LILLY AND COMPANY | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153764-A1 | Process for preparing 4-substituted piperidines | PDGFRA, GTF3C5, GRIA4 | HTR1A 316/4885SLC6A4 1890/4885KDM4E 563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.