Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.44 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7143732 | 0.87 | L3MBTL1 (0.46) | DAOLMNAHTTSYKAURKB | |
| SCHEMBL4321171 | 0.76 | POLB (0.56) | DAOLMNAALDH1A1KMT2APOLB | |
| SCHEMBL7144129 | 0.76 | FNTA (0.55) | KMT2ARAB9A | |
| SCHEMBL29405082 | 0.72 | NPC1 (0.59) | DAOLMNAALDH1A1CYP1A2TSHR | |
| SCHEMBL432670 | 0.72 | NPC1 (0.59) | DAOLMNAALDH1A1CYP1A2TSHR | |
| SCHEMBL3443470 | 0.71 | LMNA (0.44) | LMNAHTTSYKAURKBINCENP | |
| SCHEMBL9360323 | 0.70 | DAO (0.56) | DAOLMNAALDH1A1HPGDCYP1A2 | |
| SCHEMBL9656225 | 0.70 | DAO (0.55) | DAOLMNAALDH1A1KMT2ACYP1A2 | |
| SCHEMBL11177471 | 0.69 | GRM5 (0.50) | DAOLMNAHTTSYKALDH1A1 | |
| SCHEMBL10334618 | 0.67 | ACMSD (0.62) | ALDH1A1KMT2AMCL1PTPN1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0873123-B1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2003-04-09 | — | — | EP | disclosed |