Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | NQO2 | P16083 | 1/20 | 0.50 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.48 |
| ▸ | TUBB | P07437 | 4/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2651010 | 0.87 | PTGS2 (0.44) | AMY1AHPGDSMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL4452968 | 0.81 | HPGD (0.56) | AMY1AHPGDSMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL4452966 | 0.81 | HPGD (0.56) | AMY1AHPGDSMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL27955374 | 0.79 | HPGD (0.54) | AMY1AHPGDSMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL15463039 | 0.79 | HPGD (0.59) | AMY1AHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3471744 | 0.79 | HPGD (0.59) | AMY1AHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL3471747 | 0.79 | HPGD (0.59) | AMY1AHPGDSMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL25322838 | 0.78 | AMY1A (0.53) | AMY1AHPGDSMN1; SMN2PTGS2ALDH1A1 | |
| SCHEMBL14047576 | 0.78 | ALDH1A1 (0.57) | PTGS2ALDH1A1KDM4EGAAMAPT | |
| SCHEMBL3869469 | 0.78 | ALDH1A1 (0.57) | PTGS2ALDH1A1KDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030158237-A1 | Combination of antioxidant substances for the treatment of alzheimer's disease | COLBA R & D INC. (CA) | 2003-08-21 | — | — | US | disclosed |