Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 7/20 | 0.42 |
| ▸ | BCHE | P06276 | 6/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11463950 | 0.85 | CES2 (0.60) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL11465498 | 0.82 | KDM4E (0.51) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL10868413 | 0.81 | HSD17B10 (0.54) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL10774367 | 0.80 | ACHE (0.51) | ACHEBCHEHTR2ASLC6A4KCNH2 | |
| SCHEMBL9270826 | 0.76 | ALDH1A1 (0.69) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL27492169 | 0.74 | ACHE (0.43) | KMT2AACHEBCHE | |
| SCHEMBL15339832 | 0.74 | CES2 (0.64) | CES2ACHEALDH1A1NCEH1 | |
| SCHEMBL25278077 | 0.73 | MAPT (0.58) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL25275004 | 0.73 | L3MBTL1 (0.58) | KMT2AMEN1MAPTKDM4EL3MBTL1 | |
| SCHEMBL28023340 | 0.73 | GAA (0.58) | KMT2AMEN1MAPTKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1305295-A1 | IMIDAZOLE DERIVATIVES | Pfizer Products Inc. (US) | 2003-05-02 | — | — | EP | disclosed |
| WO-2002010141-A1 | IMIDAZOLE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2002-02-07 | — | — | WO | disclosed |