Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 7/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1027335 | 0.97 | SIGMAR1 (0.52) | SIGMAR1IDO1CA1CA2DRD2 | |
| Hydrochloric Acid SCHEMBL10462131 | 0.91 | SIGMAR1 (0.47) | SIGMAR1IDO1CA1CA2DRD2 | |
| SCHEMBL4606877 | 0.84 | MTNR1A (0.61) | SIGMAR1CA1CA2DRD2DRD3 | |
| SCHEMBL29599386 | 0.84 | MTNR1A (0.61) | SIGMAR1CA1CA2DRD2DRD3 | |
| SCHEMBL823057 | 0.84 | MTNR1A (0.61) | SIGMAR1CA1CA2DRD2DRD3 | |
| SCHEMBL823055 | 0.84 | MTNR1A (0.61) | SIGMAR1CA1CA2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL1026136 | 0.83 | MTNR1A (0.59) | SIGMAR1CA1CA2DRD2DRD3 | |
| SCHEMBL10513266 | 0.83 | SIGMAR1 (0.45) | SIGMAR1DRD2DRD3DRD4SLC6A2 | |
| Hydrochloric Acid SCHEMBL7430755 | 0.83 | MTNR1A (0.59) | SIGMAR1CA1CA2DRD2DRD3 | |
| Hydrochloric Acid SCHEMBL10463559 | 0.81 | SIGMAR1 (0.44) | SIGMAR1DRD2DRD3DRD4SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4782252-B2 | — | — | 2011-09-28 | — | — | JP | claimed |
| EP-0738149-A4 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMA (IL) | 1999-10-27 | — | — | EP | claimed |
| EP-0738149-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1996-10-23 | — | — | EP | claimed |
| WO-1995018617-A1 | 1-AMINOINDAN DERIVATIVES AND COMPOSITIONS THEREOF | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 1995-07-13 | — | — | WO | claimed |
| CN-115348959-B | Heteroaryl compounds and their therapeutic use in conditions associated with altered beta-glucocerebrosidase activity | GT增益治疗股份有限公司 | 2025-01-07 | — | — | CN | disclosed |
| CN-118804911-A | Acrylamide compound | NRG治疗有限公司 | 2024-10-18 | — | — | CN | disclosed |
| WO-2024141998-A1 | METHOD OF TREATING TAUOPATHIES | GT GAIN THERAPEUTICS SA (CH) | 2024-07-04 | — | — | WO | disclosed |
| US-20240190809-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AWAKN LS EUROPE HOLDINGS LIMITED (IE) | 2024-06-13 | — | — | US | disclosed |
| EP-4337316-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | Awakn Ls Europe Holdings Limited (IE) | 2024-03-20 | — | — | EP | disclosed |
| US-20230312481-A1 | SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF | ARBUTUS BIOPHARMA CORP (CA) | 2023-10-05 | — | — | US | disclosed |
| US-20230167104-A1 | NEW IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 | PERHA PHARMACEUTICALS (FR) | 2023-06-01 | — | — | US | disclosed |
| WO-2023081967-A1 | COMPOUNDS AND USES THEREFOR | THE UNIVERSITY OF WESTERN AUSTRALIA (AU) | 2023-05-19 | — | — | WO | disclosed |
| EP-0447292-A1 | 4-Aminomethyl-piperidine derivatives, their preparation and therapeutic application | SYNTHELABO (FR) | 1991-09-18 | — | — | EP | disclosed |
| US-5006561-A | Indane sulfonamide anti-arrhythmic agents and use | PFIZER INC. (US) | 1991-04-09 | — | — | US | disclosed |
| EP-0286277-B1 | ANTIARRYTHMIC AGENTS | Pfizer Limited (GB) | 1990-06-20 | — | — | EP | disclosed |
| CN-1038449-A | Antiarrhythmics | PFIZER LTD (GB) | 1990-01-03 | — | — | CN | disclosed |
| US-4829071-A | Quinolyl substituted indane sulfonamides and their use as anti-arrhythmic agents | PFIZER INC. (US) | 1989-05-09 | — | — | US | disclosed |
| EP-0286277-A1 | Antiarrythmic agents | Pfizer Limited (GB) | 1988-10-12 | — | — | EP | disclosed |
| EP-0286278-A1 | Indanamine derivatives useful as antiarrhythmic agents | Pfizer Limited (GB) | 1988-10-12 | — | — | EP | disclosed |
| EP-0144235-A2 | N6-(1- and 2-benzocycloalkyl) adenosines, pharmaceutical compositions comprising the same and a process for the production thereof | WARNER-LAMBERT COMPANY (US) | 1985-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240190809-A1 | THERAPEUTIC AMINOINDANE COMPOUNDS AND COMPOSITIONS | AADAT, PNMT, SLC1A2 | SIGMAR1 197/4885IDO1 228/4885CA1 3455/4885 |
| US-20230312481-A1 | SUBSTITUTED (PHTHALAZIN-1-YLMETHYL)UREAS, SUBSTITUTED N-(PHTHALAZIN-1-YLMETHYL)AMIDES, AND ANALOGUES THEREOF | NSD3, PML, NSD1 | SIGMAR1 4233/4885IDO1 714/4885CA1 4756/4885 |
| US-20230167104-A1 | NEW IMIDAZOLONE DERIVATIVES AS INHIBITORS OF PROTEIN KINASES IN PARTICULAR DYRK1A, CLK1 AND/OR CLK4 | CLK1, CLK2, CLK3 | SIGMAR1 3090/4885IDO1 981/4885CA1 3437/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.