SCHEMBL714543

SCHEMBL714543

CC(C)=Nc1cccc(N=C(C)C)c1

nearest known ligand 0.68

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 14/20 0.68
NOS2 P35228 2/20 0.47
HTR3E A5X5Y0 4/20 0.46
HTR3B O95264 4/20 0.46
HTR3A P46098 4/20 0.46
HTR3D Q70Z44 4/20 0.46
HTR3C Q8WXA8 4/20 0.46
NOS3 P29474 2/20 0.44
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
PLAU P00749 1/20 0.41
TAAR1 Q96RJ0 1/20 0.41
ESR1 P03372 1/20 0.39
ESR2 Q92731 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21241357 0.85 HTR3E (0.67) NOS1HTR3EHTR3BHTR3AHTR3D
SCHEMBL14269525 0.84 HTR3E (0.64) NOS1NOS2HTR3EHTR3BHTR3A
SCHEMBL486925 0.80 NOS1 (0.67) NOS1NOS2HTR3EHTR3BHTR3A
SCHEMBL26208561 0.79 CRHR1 (0.50) NOS1NOS2HTR3EHTR3BHTR3A
SCHEMBL26208548 0.77 NOS1 (0.44) NOS1NOS2HTR3EHTR3BHTR3A
SCHEMBL26208554 0.77 APP (0.44) NOS1NOS2NOS3
SCHEMBL12553932 0.76 HTR3E (0.50) NOS1NOS2HTR3EHTR3BHTR3A
SCHEMBL9059963 0.76 NOS1 (0.58) NOS1NOS2HTR3EHTR3BHTR3A
SCHEMBL1932170 0.75 NOS1 (0.58) NOS1NOS2HTR3EHTR3BHTR3A
SCHEMBL15073411 0.74 NOS1 (0.56) NOS1NOS2HTR3EHTR3BHTR3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9732232-B2 Abrasion resistant coatings HONTEK CORPORATION (US) 2017-08-15 US claimed
EP-1753798-B1 ABRASION RESISTANT COATINGS HONTEK CORP (US) 2021-01-27 EP disclosed
US-10557038-B2 Erosion resistant coatings HONTEK CORPORATION (US) 2020-02-11 US disclosed
US-20180002530-A1 EROSION RESISTANT COATINGS HONTEK CORPORATION (US) 2018-01-04 US disclosed
US-9732232-B2 Abrasion resistant coatings HONTEK CORPORATION (US) 2017-08-15 US disclosed
US-9663663-B2 Airfoil leading edge coatings HONTEK CORPORATION (US) 2017-05-30 US disclosed
US-20140039119-A1 ABRASION RESISTANT COATINGS HONTEK CORPORATION 2014-02-06 US disclosed
US-8557388-B2 Erosion resistant coatings for leading edges of airfoils HONTEK CORPORATION (US) 2013-10-15 US disclosed
US-20120279640-A1 METHOD OF MAKING EROSION RESISTANT COATINGS HONTEK CORPORATION (US) 2012-11-08 US disclosed
US-8178205-B2 Matte topcoat airfoil coatings HONTEK CORPORATION (US) 2012-05-15 US disclosed
US-20100255279-A1 ABRASION RESISTANT COATINGS HONTEK CORPORATION (US) 2010-10-07 US disclosed
US-20100249295-A1 ABRASION RESISTANT COATINGS HONTEK CORPORATION (US) 2010-09-30 US disclosed
US-7736745-B2 Abrasion resistant coatings HONTEK CORPORATION (US) 2010-06-15 US disclosed
EP-1753798-A1 ABRASION RESISTANT COATINGS Hontek Corporation (US) 2007-02-21 EP disclosed
WO-2006055038-A1 ABRASION RESISTANT COATINGS HONTEK CORPORATION (US) 2006-05-26 WO disclosed
US-20050271881-A1 Abrasion resistant coatings HONTEK CORPORATION 2005-12-08 US disclosed
US-5786437-A BLOCKING PHENOL IS RAPIDLY DISPLACED BY AN AMINE GROUP IN LESS THAN ONE-HALF THE TIME REQUIRED FOR AN ANALOGOUS SEALANT IN WHICH END-CAPPING IS PERFORMED WITH AN AROMATIC POLYISOCYANATE TREMCO INCORPORATED (US) 1998-07-28 US disclosed
EP-0156165-B1 SEALANT AND COATING COMPOSITION TREMCO INCORPORATED (US) 1988-04-20 EP disclosed
EP-0156165-A1 Sealant and coating composition TREMCO INCORPORATED (US) 1985-10-02 EP disclosed
US-4507443-A Sealant and coating composition THE B. F. GOODRICH COMPANY (US) 1985-03-26 US disclosed