Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | IDH2 | P48735 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24627913 | 0.82 | MAPK1 (0.33) | MAPK1ALDH1A1TAAR1ALOX15 | |
| SCHEMBL4872496 | 0.79 | ALDH1A1 (0.36) | MAPK1ALDH1A1TSHRMAPTMEN1 | |
| SCHEMBL8847011 | 0.77 | MAPK1 (0.38) | MAPK1ALDH1A1TSHRMAPTTAAR1 | |
| SCHEMBL14838581 | 0.77 | ALDH1A1 (0.38) | MAPK1ALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL9887940 | 0.76 | MAPK1 (0.36) | MAPK1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL15070917 | 0.75 | ALDH1A1 (0.35) | MAPK1ALDH1A1TSHRMAPTKMT2A | |
| SCHEMBL20219146 | 0.75 | ALDH1A1 (0.31) | MAPK1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL2856185 | 0.72 | KIF11 (0.50) | MAPK1ALDH1A1TSHRMEN1KMT2A | |
| SCHEMBL179890 | 0.72 | MAPK1 (0.33) | MAPK1ALDH1A1ALOX15 | |
| SCHEMBL28886036 | 0.71 | ALDH1A1 (0.40) | MAPK1ALDH1A1TSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220161245-A1 | Compositions And Methods For Infrared-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2022-05-26 | — | — | US | disclosed |
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2022-05-17 | — | — | US | disclosed |
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-08 | — | — | US | disclosed |
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2018-03-08 | — | — | US | disclosed |
| US-9815765-B2 | Ruthenium polymerisation catalysts | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2017-11-14 | — | — | US | disclosed |
| US-9815765-B2 | Ruthenium polymerisation catalysts | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2017-11-14 | — | — | US | disclosed |
| US-9233994-B2 | Ruthenium complexes for use in olefin metathesis | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2016-01-12 | — | — | US | disclosed |
| US-9233994-B2 | Ruthenium complexes for use in olefin metathesis | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2016-01-12 | — | — | US | disclosed |
| US-20140228563-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2014-08-14 | — | — | US | disclosed |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2013-06-27 | — | — | US | disclosed |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2013-06-27 | — | — | US | disclosed |
| WO-2013045876-A1 | RUTHENIUM POLYMERISATION CATALYSTS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2013-04-04 | — | — | WO | disclosed |
| WO-2011117571-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS (GB) | 2011-09-29 | — | — | WO | disclosed |
| WO-2010040939-A1 | NOVEL METHOD FOR THE METATHESIS OF OLEFINS OR ENYNES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2010-04-15 | — | — | WO | disclosed |
| US-6590048-B1 | Catalysts comprising group VIII compounds used for cyclization of crown ethers, antibiotics, veterinary medicines or perfumes | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2003-07-08 | — | — | US | disclosed |
| EP-1037897-B1 | HIGHLY ACTIVE CATIONIC RUTHENIUM AND OSMIUM COMPLEXES FOR OLEFIN METATHESIS REACTIONS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 2002-06-12 | — | — | EP | disclosed |
| EP-1037897-A1 | HIGHLY ACTIVE CATIONIC RUTHENIUM AND OSMIUM COMPLEXES FOR OLEFIN METATHESIS REACTIONS | Studiengesellschaft Kohle mbH (DE) | 2000-09-27 | — | — | EP | disclosed |
| WO-1999028330-A1 | HIGHLY ACTIVE CATIONIC RUTHENIUM AND OSMIUM COMPLEXES FOR OLEFIN METATHESIS REACTIONS | STUDIENGESELLSCHAFT KOHLE MBH (DE) | 1999-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11331656-B2 | Compositions and methods for visible-light-controlled ruthenium-catalyzed olefin metathesis | PPOX, CYBA, CYBB | MAPK1 4079/4885ALDH1A1 1395/4885TSHR 4806/4885 |
| US-20220161245-A1 | Compositions And Methods For Infrared-Light-Controlled Ruthenium-Catalyzed Olefin Metathesis | CYBB, CYBA, CYB5R3 | MAPK1 3759/4885ALDH1A1 714/4885TSHR 4665/4885 |
| US-20180065914-A1 | RUTHENIUM POLYMERISATION CATALYSTS | RRP12, PCBP1, PARG | MAPK1 3211/4885ALDH1A1 4132/4885TSHR 3395/4885 |
| US-20130165649-A1 | RUTHENIUM COMPLEXES FOR USE IN OLEFIN METATHESIS | OSBP, CYCS, OSBPL3 | MAPK1 3588/4885ALDH1A1 4330/4885TSHR 2801/4885 |
| US-20140228563-A1 | RUTHENIUM POLYMERISATION CATALYSTS | RRP12, PCBP1, PARG | MAPK1 3211/4885ALDH1A1 4132/4885TSHR 3395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.