Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.64 |
| ▸ | MEN1 | O00255 | 11/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 11/20 | 0.64 |
| ▸ | MAPT | P10636 | 8/20 | 0.64 |
| ▸ | THRB | P10828 | 7/20 | 0.64 |
| ▸ | RECQL | P46063 | 5/20 | 0.64 |
| ▸ | S100A4 | P26447 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.58 |
| ▸ | FGB | P02675 | 1/20 | 0.58 |
| ▸ | PPARG | P37231 | 1/20 | 0.58 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.58 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.58 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13856691 | 0.76 | MEN1 (1.00) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL25214434 | 0.73 | F7 (0.48) | ALDH1A1MAPTPOLB | |
| SCHEMBL4662757 | 0.72 | CA9 (0.50) | MEN1KMT2APOLBLMNA | |
| SCHEMBL4882690 | 0.72 | BRPF1 (0.45) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL715498 | 0.72 | ADRA2B (0.47) | ALDH1A1MAPTHTTTDP1HSD17B10 | |
| SCHEMBL715945 | 0.72 | MAPT (0.51) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL714553 | 0.71 | ACLY (0.38) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL435737 | 0.71 | RXFP1 (0.47) | ALDH1A1MEN1KMT2AMAPTTHRB | |
| SCHEMBL25213233 | 0.71 | AHR (0.48) | POLB | |
| SCHEMBL904754 | 0.70 | CA1 (0.42) | ALDH1A1MEN1KMT2AMAPTTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052057-A9 | METHOD FOR SELECTING RESPONDERS TO BLOCKADE OF INTEGRIN RECEPTORS | BIOTIE THERAPIES CORPORATION (FI) | 2012-03-01 | — | — | US | claimed |
| US-20110150859-A1 | METHOD FOR SELECTING RESPONDERS TO BLOCKADE OF INTEGRIN RECEPTORS | BIOTIE THERAPIES CORPORATION (FI) | 2011-06-23 | — | — | US | claimed |