Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 4/20 | 0.38 |
| ▸ | PHGDH | O43175 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.37 |
| ▸ | MEN1 | O00255 | 5/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | S100A4 | P26447 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4882690 | 0.73 | BRPF1 (0.45) | ACLYALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL435737 | 0.72 | RXFP1 (0.47) | ACLYALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL714554 | 0.71 | ALDH1A1 (0.64) | ALDH1A1MEN1MAPTKMT2APTGDR | |
| SCHEMBL715944 | 0.71 | ALDH1A1 (0.46) | ALDH1A1MEN1MAPTKMT2AKDM4E | |
| SCHEMBL715496 | 0.69 | ADRA2B (0.43) | MAPTKMT2AKDM4ETDP1GAA | |
| SCHEMBL23866836 | 0.66 | MEN1 (0.44) | ALDH1A1MEN1MAPTKMT2ATHRB | |
| SCHEMBL13797489 | 0.64 | TRPV4 (0.48) | ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL28861312 | 0.62 | CA12 (0.54) | ALDH1A1MEN1MAPTKMT2ATHRB | |
| SCHEMBL23251426 | 0.62 | TRPV4 (0.47) | ALDH1A1MAPTTDP1 | |
| SCHEMBL10222171 | 0.62 | PSMB8 (0.42) | ALDH1A1MEN1MAPTKMT2ATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120052057-A9 | METHOD FOR SELECTING RESPONDERS TO BLOCKADE OF INTEGRIN RECEPTORS | BIOTIE THERAPIES CORPORATION (FI) | 2012-03-01 | — | — | US | claimed |
| US-20110150859-A1 | METHOD FOR SELECTING RESPONDERS TO BLOCKADE OF INTEGRIN RECEPTORS | BIOTIE THERAPIES CORPORATION (FI) | 2011-06-23 | — | — | US | claimed |