Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HNF4A | P41235 | 2/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.38 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 3/20 | 0.38 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.36 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.36 |
| ▸ | FABP3 | P05413 | 3/20 | 0.34 |
| ▸ | FABP4 | P15090 | 3/20 | 0.34 |
| ▸ | FABP5 | Q01469 | 2/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | PRNP | P04156 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17310619 | 0.81 | HNF4A (0.42) | HNF4APTPN1PTPN6FOLH1PTPN2 | |
| SCHEMBL1950689 | 0.79 | LMNA (0.41) | RXRAPDE4BPDE4DNR4A2FABP3 | |
| SCHEMBL6278249 | 0.78 | HNF4A (0.53) | HNF4APTPN1PTPN6FOLH1PTPN2 | |
| SCHEMBL50362 | 0.77 | HNF4A (0.50) | HNF4APTPN1PTPN6FOLH1PTPN2 | |
| SCHEMBL6255456 | 0.76 | RXRA (0.42) | HNF4ARXRAPDE4BPDE4DNR4A2 | |
| SCHEMBL7637844 | 0.75 | RARB (0.45) | MCL1PPARG | |
| SCHEMBL29078171 | 0.75 | PDCD1 (0.40) | — | |
| SCHEMBL11236463 | 0.74 | GPR35 (0.54) | AKR1C3AKR1C2AKR1C1NR4A2RXFP1 | |
| SCHEMBL21449049 | 0.74 | SRD5A2 (0.40) | PPARGTSHR | |
| SCHEMBL29443090 | 0.74 | HNF4A (0.50) | HNF4APTPN1PTPN6FOLH1PTPN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973811-B1 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING SA (FR) | 2003-01-15 | — | — | EP | disclosed |
| US-6476103-B1 | Photochromic organic material, its manufacture and the photochromic articles containing it | CORNING INCORPORATED | 2002-11-05 | — | — | US | disclosed |
| US-6316569-B1 | RESISTANCE TO PHOTO-FATIGUE; FOR OPHTHALMIC APPLICATIONS | CORNING S.A. (FR) | 2001-11-13 | — | — | US | disclosed |
| EP-0973811-A4 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING SA (FR) | 2000-07-12 | — | — | EP | disclosed |
| EP-0973811-A1 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING INCORPORATED (US) | 2000-01-26 | — | — | EP | disclosed |
| EP-0931278-A4 | PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT | CORNING INC (US) | 1999-12-29 | — | — | EP | disclosed |
| EP-0931278-A1 | PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT | CORNING INCORPORATED (US) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998045341-A1 | SELF-LIGHT-STABILIZED PHOTOCHROMIC POLYMER, ITS PREPARATION AND ARTICLES CONTAINING SAME | CORNING INCORPORATED (US) | 1998-10-15 | — | — | WO | disclosed |
| WO-1998016863-A1 | PHOTOCHROMIC ORGANIC MATERIAL, ITS MANUFACTURE AND THE PHOTOCHROMIC ARTICLES CONTAINING IT | CORNING INCORPORATED (US) | 1998-04-23 | — | — | WO | disclosed |