Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.55 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.55 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.51 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.49 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.49 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.49 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.49 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.49 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.49 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6546257 | 0.98 | ALDH1A1 (0.53) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL7140967 | 0.90 | SMN1; SMN2 (0.51) | ALDH1A1APPGAAHCAR3HCAR2 | |
| Bromide SCHEMBL6282444 | 0.89 | SMN1; SMN2 (0.50) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL627867 | 0.82 | CES2 (0.64) | ALDH1A1HTTCES2CES1LMNA | |
| SCHEMBL11065543 | 0.81 | LMNA (0.67) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL3115655 | 0.81 | MEN1 (0.52) | ALDH1A1PLOD2EPHX2CYP2C9CYP2C19 | |
| SCHEMBL19104771 | 0.81 | CES2 (0.53) | ALDH1A1PLOD2EPHX2CYP2C9CYP2C19 | |
| SCHEMBL7262916 | 0.80 | ALDH1A1 (0.59) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL11283641 | 0.80 | ALDH1A1 (0.55) | ALDH1A1APPGAAHCAR3HCAR2 | |
| SCHEMBL11820789 | 0.80 | ALDH1A1 (0.55) | ALDH1A1APPGAAHCAR3HCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620825-B1 | 1,3-Azole compound substituted by pyridyl; administering as antiasthmatic, antiinflammatory or antiallergen agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| US-6436966-B1 | Adenosine A3 receptor antagonists | TAKEDA CHEMICAL IND., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |
| WO-1983002613-A1 | TRISUBSTITUTED OXAZO COMPOUNDS | SALLMANN, ALFRED | 1983-08-04 | — | — | WO | disclosed |
| EP-0084756-A1 | Trisubstituted oxaza compounds | CIBA-GEIGY AG (CH) | 1983-08-03 | — | — | EP | disclosed |
| EP-0082111-A2 | Process for the preparation of imidazoles | CIBA-GEIGY AG (CH) | 1983-06-22 | — | — | EP | disclosed |
| EP-0046451-A2 | Diaryl-imidazole compounds, methods for their preparation, pharmaceutical drugs containing them and their use | CIBA-GEIGY AG (CH) | 1982-02-24 | — | — | EP | disclosed |