Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CCR2 | P41597 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7615169 | 0.85 | MEN1 (0.43) | MEN1KMT2AMAOBMAOACCR2 | |
| SCHEMBL6326374 | 0.84 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2MAOBMAOA | |
| SCHEMBL7024973 | 0.83 | MEN1 (0.48) | MEN1KMT2ASMN1; SMN2MAOBOPRK1 | |
| SCHEMBL6320217 | 0.75 | SMN1; SMN2 (0.46) | MEN1KMT2ASMN1; SMN2OPRK1OPRM1 | |
| SCHEMBL7032860 | 0.74 | SMN1; SMN2 (0.43) | MEN1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL11125959 | 0.74 | SMN1; SMN2 (0.57) | MEN1KMT2ASMN1; SMN2OPRK1SIGMAR1 | |
| SCHEMBL17073435 | 0.72 | SIGMAR1 (0.49) | SMN1; SMN2CCR2OPRM1SIGMAR1TSHR | |
| SCHEMBL31067545 | 0.72 | SIGMAR1 (0.49) | SMN1; SMN2CCR2OPRM1SIGMAR1TSHR | |
| SCHEMBL6320470 | 0.71 | CALM1 (0.47) | MEN1KMT2ASMN1; SMN2OPRK1SIGMAR1 | |
| SCHEMBL17065048 | 0.71 | CHRM3 (0.52) | SMN1; SMN2CCR2OPRM1SIGMAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030032834-A1 | Aminoalcohol derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030032834-A1 | Aminoalcohol derivatives | ADRB1, ADRB2, ADRB3 | MEN1 4166/4885KMT2A 3486/4885SMN1; SMN2 3568/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.