Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 1/20 | 0.44 |
| ▸ | PGK2 | P07205 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | BRS3 | P32247 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1550855 | 0.81 | PGK1 (0.38) | PGK1PGK2HSD11B1ALDH1A1LMNA | |
| Trifluoromethanesulfonic Acid SCHEMBL6282631 | 0.80 | SMN1; SMN2 (0.46) | HSD11B1ALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| Trifluoromethanesulfonic Acid SCHEMBL3488688 | 0.79 | SDHB (0.36) | PGK1PGK2ALDH1A1LMNAGAA | |
| SCHEMBL42955 | 0.78 | PGK1 (0.39) | PGK1PGK2ALDH1A1LMNAGAA | |
| SCHEMBL12553835 | 0.77 | PGK1 (0.42) | PGK1PGK2ACHETSHRCA2 | |
| SCHEMBL2609323 | 0.77 | IDH1 (0.49) | PGK1PGK2P2RX7KDM4E | |
| Iodide SCHEMBL2346492 | 0.76 | PGK1 (0.38) | PGK1PGK2ALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL30595152 | 0.76 | PGK1 (0.38) | PGK1PGK2ALDH1A1LMNAGAA | |
| Trifluoromethanesulfonic Acid SCHEMBL28461783 | 0.76 | HSD11B1 (0.44) | HSD11B1ALDH1A1GAAP2RX7KDM4E | |
| SCHEMBL28748272 | 0.74 | PGK1 (0.39) | PGK1PGK2ACHEALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823196-A | Glycoside and preparation method thereof | 南开大学 | 2025-04-15 | — | — | CN | claimed |
| CN-119823196-A | Glycoside and preparation method thereof | 南开大学 | 2025-04-15 | — | — | CN | disclosed |
| US-6586441-B2 | 2-Amino-6-benzylsulfanyl-4-thiophen-2-yl-pyridine-3,5-dicarbo -nitrile as an examplary preferred compound; Alzheimer's and Parkinson's diseases; neuroprotectors; schizophrenia, analgesics; anxiolytic agents; respiratory disorders | HOFFMAN-LA ROCHE INC. | 2003-07-01 | — | — | US | disclosed |
| EP-1261327-A2 | ADENOSINE RECEPTOR MODULATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2002-12-04 | — | — | EP | disclosed |
| US-20010027196-A1 | Adenosine receptor ligands and their use in the treatment of disease | F. HOFFMANN-LA ROCHE AG (CH) | 2001-10-04 | — | — | US | disclosed |
| WO-2001062233-A2 | ADENOSINE RECEPTOR MODULATORS | F. HOFFMANN LA ROCHE AG (CH) | 2001-08-30 | — | — | WO | disclosed |
| US-5830969-A | ANHYDROUS MIXTURE CONTAINING LEWIS BASE | DOW CORNING CORPORATION (US) | 1998-11-03 | — | — | US | disclosed |
| EP-0854162-A2 | Silyl ester initiators for ring opening polymerization of cyclosiloxanes | DOW CORNING CORPORATION (US) | 1998-07-22 | — | — | EP | disclosed |
| US-5696219-A | Silyl ester initiators for cyclosiloxane ring opening polymerization | DOW CORNING CORPORATION (US) | 1997-12-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010027196-A1 | Adenosine receptor ligands and their use in the treatment of disease | ADORA2A, ADORA2B, ADORA1 | PGK1 2651/4885PGK2 2863/4885HSD11B1 2977/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.