SCHEMBL7150552

SCHEMBL7150552

CNc1ccc(S(=O)(=O)c2ccccc2C)cc1C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 2/20 0.51
HSD11B1 P28845 1/20 0.46
ABCC9 O60706 1/20 0.43
ABCC8 Q09428 1/20 0.43
KCNJ11 Q14654 1/20 0.43
KCNJ8 Q15842 1/20 0.43
KDM4E B2RXH2 3/20 0.40
LMNA P02545 2/20 0.40
TSHR P16473 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
NAMPT P43490 2/20 0.39
ALDH1A1 P00352 3/20 0.39
GAA P10253 1/20 0.39
PKM P14618 1/20 0.39
MAPT P10636 2/20 0.38
HTT P42858 1/20 0.38
POLB P06746 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
SFRP1 Q8N474 1/20 0.38
CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6535792 0.83 KMT2A (0.57) HTR6ALDH1A1GAAPKMMAPT
SCHEMBL29039876 0.81 ALDH1A1 (0.56) HSD11B1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL30513969 0.81 ALDH1A1 (0.56) HSD11B1ABCC9ABCC8KCNJ11KCNJ8
SCHEMBL28835290 0.78 ABCC9 (0.56) HTR6HSD11B1ABCC9ABCC8KCNJ11
SCHEMBL17146965 0.75 ALDH1A1 (0.42) LMNAALDH1A1MAPTSMN1; SMN2
SCHEMBL13241569 0.75 LMNA (0.52) HSD11B1KDM4ELMNATSHRL3MBTL1
SCHEMBL14364002 0.74 SNCA (0.44) KDM4ELMNATSHRALDH1A1GAA
SCHEMBL3223324 0.74 CA2 (0.52) HTTPOLB
SCHEMBL2068969 0.73 ALDH1A1 (0.53) HTR6HSD11B1ABCC9ABCC8KCNJ11
SCHEMBL28722634 0.73 HSD11B1 (0.48) HSD11B1ABCC9ABCC8KCNJ11KCNJ8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0620929-B1 PHOTOGRAPHIC DISPERSION EASTMAN KODAK CO (US) 2003-10-01 EP disclosed
EP-0661588-B1 Color photographic element EASTMAN KODAK CO (US) 1999-10-20 EP disclosed
US-5468604-A Particle growth inhibition EASTMAN KODAK COMPANY (US) 1995-11-21 US disclosed
EP-0661588-A2 Color photographic element EASTMAN KODAK COMPANY (US) 1995-07-05 EP disclosed