Known targets — ChEMBL curated mechanism
ABL1BMXBRAFBTKCHRNA4CHRNB2CSNK1EEGFRERBB2F10FLT1FLT3FLT4IGF1RINSRITKJAK3KDRKITOPRM1PARP1PARP2PDGFRBPIK3CDRAF1RETSLC18A2TECTXKdacAdacBdacCftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.44 |
| ▸ | CA9 | Q16790 | 2/20 | 0.44 |
| ▸ | CA3 | P07451 | 1/20 | 0.44 |
| ▸ | CA6 | P23280 | 1/20 | 0.44 |
| ▸ | CA5A | P35218 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22090243 | 0.89 | CYP2D6 (0.47) | CYP2D6MAPK1ALDH1A1MAPTTDP1 | |
| SCHEMBL22089693 | 0.89 | CYP2D6 (0.47) | CYP2D6MAPK1ALDH1A1MAPTTDP1 | |
| SCHEMBL22089696 | 0.89 | CYP2D6 (0.47) | CYP2D6MAPK1ALDH1A1MAPTTDP1 | |
| SCHEMBL31504465 | 0.85 | ALDH1A1 (0.50) | CYP2D6MAPK1ALDH1A1MAPTTDP1 | |
| SCHEMBL8976348 | 0.83 | CYP2D6 (0.46) | CYP2D6MAPK1ALDH1A1MAPTTDP1 | |
| Acetonitrile SCHEMBL17474635 | 0.83 | ALDH1A1 (0.52) | CYP2D6MAPK1ALDH1A1MAPTTDP1 | |
| Acetonitrile SCHEMBL29256909 | 0.83 | ALDH1A1 (0.52) | CYP2D6MAPK1ALDH1A1MAPTTDP1 | |
| Acetonitrile SCHEMBL318491 | 0.83 | ALDH1A1 (0.52) | CYP2D6MAPK1ALDH1A1MAPTTDP1 | |
| Isopropylamine SCHEMBL2350740 | 0.83 | CYP2D6 (0.53) | CYP2D6MAPK1ALDH1A1MAPTTDP1 | |
| Water SCHEMBL5350 | 0.82 | GAA (0.59) | CYP2D6MAPK1ALDH1A1MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119083178-A | Preparation method of anticoagulant coating on surface of polyester fiber fabric | 浙江理工大学 | 2024-12-06 | — | — | CN | claimed |
| CN-118725657-A | Preparation method of functional coating based on aminopropiodinitrile self-polymerization | 浙江理工大学 | 2024-10-01 | — | — | CN | claimed |
| CN-117018884-A | Super-hydrophilic self-cleaning separation membrane and preparation method thereof | 哈尔滨工业大学 | 2023-11-10 | — | — | CN | claimed |
| CN-115746213-A | Anti-fouling resin and preparation method thereof | 深圳市通泰盈科技股份有限公司 | 2023-03-07 | — | — | CN | claimed |
| EP-0003335-B1 | PROCESS FOR PREPARING AMINOMALONIC ACID DINITRILE TOSYLAT OR ACETYLAMINOMALONIC ACID DINITRIL | LONZA AG (CH) | 1981-07-01 | — | — | EP | claimed |
| CN-122080069-A | Phospholipid compounds and uses thereof | — | 2026-05-26 | — | — | CN | disclosed |
| US-12545652-B2 | Crystalline forms of a TYK2 inhibitor | SAREUM LIMITED (GB) | 2026-02-10 | — | — | US | disclosed |
| CN-118725657-B | Preparation method of functional coating based on aminopropiodinitrile self-polymerization | 浙江理工大学 | 2025-11-07 | — | — | CN | disclosed |
| CN-119083178-B | Preparation method of anticoagulant coating on surface of polyester fiber fabric | 浙江理工大学 | 2025-11-04 | — | — | CN | disclosed |
| US-20250288559-A1 | PREP BINDING LIGANDS | POLKU THERAPEUTICS OY (FI) | 2025-09-18 | — | — | US | disclosed |
| EP-4514781-A1 | PREP BINDING LIGANDS | Polku Therapeutics OY (FI) | 2025-03-05 | — | — | EP | disclosed |
| EP-3864009-B1 | TYK2 KINASE INHIBITORS | SAREUM LTD (GB) | 2025-02-19 | — | — | EP | disclosed |
| EP-0276329-B1 | 2,3-DIAMINOACRYLONITRILE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 1991-03-06 | — | — | EP | disclosed |
| US-4990630-A | Chemical intermediates/ | NIPPON SODA CO., LTD. (JP) | 1991-02-05 | — | — | US | disclosed |
| US-4827015-A | Process for the production of aminomalonic acid dinitrile salts | LONZA LTD. (CH) | 1989-05-02 | — | — | US | disclosed |
| EP-0298261-A1 | Process for the preparation of salts of aminomalonic dinitrile | LONZA AG (CH) | 1989-01-11 | — | — | EP | disclosed |
| EP-0276329-A1 | 2,3-DIAMINOACRYLONITRILE DERIVATIVES. | NIPPON SODA CO (JP) | 1988-08-03 | — | — | EP | disclosed |
| WO-1988001264-A1 | 2,3-DIAMINOACRYLONITRILE DERIVATIVES | NIPPON SODA CO., LTD. (JP) | 1988-02-25 | — | — | WO | disclosed |
| EP-0003335-B1 | PROCESS FOR PREPARING AMINOMALONIC ACID DINITRILE TOSYLAT OR ACETYLAMINOMALONIC ACID DINITRIL | LONZA AG (CH) | 1981-07-01 | — | — | EP | disclosed |
| US-4212818-A | Process for the production of aminomalonic acid dinitrile as an aminomalonic acid dinitriltosylate precipitate or as an acetylaminomalodinitrile precipitate | LONZA LTD. (CH) | 1980-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12545652-B2 | Crystalline forms of a TYK2 inhibitor | TYK2, PTK2B, JAK1 | CYP2D6 3471/4885MAPK1 333/4885ALDH1A1 4844/4885 |
| US-20250288559-A1 | PREP BINDING LIGANDS | PREP, ERAP2, CTSA | CYP2D6 4601/4885MAPK1 3756/4885ALDH1A1 4707/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.