Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.35 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.35 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 5/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19002947 | 0.73 | TSHR (0.50) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL30951307 | 0.73 | TSHR (0.50) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL197690 | 0.67 | ACHE (0.64) | NISCHNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL30169568 | 0.67 | ACHE (0.64) | NISCHNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL30354037 | 0.67 | ACHE (0.64) | NISCHNPC1RAB9ASMN1; SMN2CASP3 | |
| Lithium SCHEMBL31260773 | 0.64 | ACHE (0.60) | NISCHNPC1RAB9ASMN1; SMN2CASP3 | |
| Ammonia Solution, Strong SCHEMBL842431 | 0.64 | ACHE (0.60) | NISCHNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL6564122 | 0.64 | ACHE (0.60) | NISCHNPC1RAB9ASMN1; SMN2CASP3 | |
| SCHEMBL19897390 | 0.63 | TSHR (0.50) | NPC1RAB9ASMN1; SMN2CASP3SENP8 | |
| SCHEMBL277747 | 0.63 | ELANE (0.52) | NPC1RAB9ASMN1; SMN2CASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8357765-B2 | Process for producing catalyst component for addition polymerization | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-01-22 | — | — | US | disclosed |
| US-8288490-B2 | Process for producing catalyst component for addition polymerization | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-10-16 | — | — | US | disclosed |
| US-20120053311-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
| US-20120053306-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120053306-A1 | PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION | PPOX, SOD1, AP1M1 | ACHE 3049/4885NISCH 375/4885NPC1 4275/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.