Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758704 | 0.77 | KMT2A (0.56) | ALDH1A1APPKMT2AKDM4EL3MBTL1 | |
| SCHEMBL22171609 | 0.75 | ALDH1A1 (0.53) | ALDH1A1TSHRHAO1APPKMT2A | |
| SCHEMBL1878805 | 0.75 | HAO1 (0.58) | ALDH1A1TSHRHAO1APPKMT2A | |
| SCHEMBL715245 | 0.75 | HAO1 (0.49) | ALDH1A1TSHRHAO1APPKMT2A | |
| SCHEMBL12854014 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TSHRHAO1APPKMT2A | |
| SCHEMBL11947419 | 0.74 | ALDH1A1 (0.51) | ALDH1A1TSHRHAO1APPKMT2A | |
| SCHEMBL713626 | 0.72 | HAO1 (0.52) | ALDH1A1TSHRHAO1APPKMT2A | |
| SCHEMBL13425022 | 0.72 | HAO1 (0.62) | ALDH1A1TSHRHAO1APPKMT2A | |
| SCHEMBL715182 | 0.71 | ALDH1A1 (0.39) | ALDH1A1TSHRKMT2AKDM4EGSK3A | |
| SCHEMBL713625 | 0.71 | KMT2A (0.49) | ALDH1A1TSHRHAO1APPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382206-B2 | Nitrogen-containing aromatic heterocyclic derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2016-07-05 | — | — | US | disclosed |
| US-8771843-B2 | Fluorene derivative, organic compound, and light-emitting element, light-emitting device, and electronic device using the compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) | 2014-07-08 | — | — | US | disclosed |
| EP-2628729-A1 | AROMATIC HETEROCYCLIC DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2013-08-21 | — | — | EP | disclosed |
| EP-2617712-A1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING SAME | Idemitsu Kosan Co., Ltd. (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-20120273766-A1 | AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-11-01 | — | — | US | disclosed |
| US-20120181524-A1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | IDEMITSU KOSAN CO., LTD. (JP) | 2012-07-19 | — | — | US | disclosed |
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | SEMICONDUCTOR ENERGY LABORATORY CO., LTD. | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120049768-A1 | Fluorene Derivative, Organic Compound, and Light-Emitting Element, Light-Emitting Device, and Electronic Device Using the Compound | AFF2, MAPRE2, AFF4 | ALDH1A1 1391/4885TSHR 1971/4885HAO1 2831/4885 |
| US-20120181524-A1 | NITROGEN-CONTAINING AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | AOC3, NPR3, NR0B1 | ALDH1A1 1045/4885TSHR 827/4885HAO1 1814/4885 |
| US-20120273766-A1 | AROMATIC HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME | DDC, ODC1, TYR | ALDH1A1 61/4885TSHR 3948/4885HAO1 1326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.