SCHEMBL715286

SCHEMBL715286

O=C(O)c1cc2c(cc1C(=O)O)C(C(F)(F)F)(C(F)(F)F)c1cc(C(=O)O)c(C(=O)O)cc1O2

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ASPH Q12797 1/20 0.34
PDK2 Q15119 3/20 0.33
ALOX5 P09917 1/20 0.32
NOTUM Q6P988 2/20 0.32
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
HSD17B10 Q99714 1/20 0.32
RXRA P19793 1/20 0.31
RXRB P28702 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
CYP2C9 P11712 1/20 0.31
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29617167 1.00 ASPH (0.34) ASPHPDK2ALOX5NOTUMKDM4E
SCHEMBL29405016 1.00 ASPH (0.34) ASPHPDK2ALOX5NOTUMKDM4E
SCHEMBL9455649 0.97 KMT2A (0.34) ASPHPDK2ALOX5NOTUMKDM4E
SCHEMBL28922371 0.84 PDK2 (0.30) PDK2
SCHEMBL3471311 0.83 NOTUM (0.33) ASPHALOX5NOTUMKDM4EALDH1A1
SCHEMBL1099586 0.78 PDK2 (0.38) PDK2ALOX5NOTUMKDM4EALDH1A1
SCHEMBL29415487 0.77 PDK2 (0.42) PDK2KDM4EALDH1A1HSD17B10KMT2A
SCHEMBL9221863 0.77 PDK2 (0.37) PDK2ALOX5NOTUMKDM4EALDH1A1
SCHEMBL3272491 0.76 ALOX5 (0.34) ALOX5KDM4EALDH1A1RXRARXRB
SCHEMBL9220858 0.76 PDK2 (0.36) PDK2ALOX5NOTUMKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 269 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2024-02-15 US claimed
CN-102436164-B The intermediate transfer element of phosphate ester polyimide containing Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) 2016-04-20 CN claimed
US-9034423-B2 Method of making a fuser member XEROX CORPORATION (US) 2015-05-19 US claimed
US-20140178579-A1 METHOD OF MAKING A FUSER MEMBER XEROX CORPORATION (US) 2014-06-26 US claimed
US-20140171588-A1 COMPOSITION FOR FLEXIBLE SUBSTRATE AND FLEXIBLE SUBSTRATE FORMED FROM THE SAME CHI MEI CORPORATION (TW) 2014-06-19 US claimed
EP-2092807-B1 COMPOSITE ORGANIC ENCAPSULANTS CDA PROC LTD LIABILITY COMPANY (US) 2013-04-17 EP claimed
US-20120049123-A1 PHOSPHATE ESTER POLYIMIDE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2012-03-01 US claimed
US-8029901-B2 Polyaryl ether copolymer containing intermediate transfer members XEROX CORPORATION (US) 2011-10-04 US claimed
US-20100279214-A1 POLYARYL ETHER COPOLYMER CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2010-11-04 US claimed
US-7745516-B2 Composition of polyimide and sterically-hindered hydrophobic epoxy E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-29 US claimed
EP-0758000-B1 Polyimide films from pyromellitic dianhydride and 2,2'-bis(perfluoroalkoxy)benzidines as alignment layers for liquid crystal displays DU PONT (US) 2001-12-19 EP claimed
US-6316170-B2 COATING, EXPOSURE, DEVELOPMENT AND HEAT TREATMENT KABUSHIKI KAISHA TOSHIBA (JP) 2001-11-13 US claimed
US-20010006767-A1 Developing solution and method of forming polyimide pattern by using the developing solution YOSHIAKI KAWAMONZEN 2001-07-05 US claimed
US-6066400-A Polyimide biasable components XEROX CORPORATION (US) 2000-05-23 US claimed
US-5759442-A Polyimide alignment film from 2,2-BIS (3,4-dicarboxyphenyl)--hexafluoropropane dianhydride and ortho-substituted aromatic diamines for active matrix liquid crystal displays E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-06-02 US claimed
US-5731404-A Polyimide film from pyromellitic dianhydride and a bis(4-aminophenoxy) aromatic compound as an alignment layer for liquid crystal displays E. I. DU PONT DE NEMOURS AND COMPANY (US) 1998-03-24 US claimed
US-5670609-A FILMS WITH LIQUID CCRYSTAL STRUCTURE E. I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-23 US claimed
EP-0772074-A1 Polyimide film from pyromellitic dianhydride and bis(4-aminophenoxy) aromatic compound as an alignment layer for liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-05-07 EP claimed
EP-0768559-A1 Polyimide alignment film from 2,2-bis(3,4-dicarboxyphenyl)hexafluoropropane, dianhydride and ortho-substituted aromatic diamines for active matrix liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-04-16 EP claimed
EP-0758000-A2 Polyimide films from pyromellitic dianhydride and 2,2'-bis(perfluoroalkoxy)benzidines as alignment layers for liquid crystal displays E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-02-12 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240052104-A1 DICARBONYL HALIDES, POLYMER COMPOSITIONS AND FILMS MADE THEREFROM PUF60, PICALM, PARG ASPH 618/4885PDK2 3405/4885ALOX5 1327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.