Toluene

Toluene

SCHEMBL7154552

Cc1ccccc1.O=C1C=CC(=O)O1

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.55
LMNA P02545 1/20 0.55
TSHR P16473 1/20 0.55
ALOX12 P18054 1/20 0.55
CES2 O00748 1/20 0.38
CES1 P23141 1/20 0.38
HPGD P15428 5/20 0.37
MEN1 O00255 4/20 0.37
KMT2A Q03164 4/20 0.37
ALDH1A1 P00352 3/20 0.37
CYP2C9 P11712 2/20 0.37
POLB P06746 2/20 0.37
NFKB1 P19838 2/20 0.37
NFKB2 Q00653 2/20 0.37
RELA Q04206 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
KDM4E B2RXH2 2/20 0.37
CYP3A4 P08684 2/20 0.37
CYP1A2 P05177 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
P-Xylene SCHEMBL27790320 0.87 ACHE (0.47) ACHELMNACES2CES1HPGD
O-Xylene SCHEMBL27285203 0.82 TSHR (0.53) ACHETSHRHPGDMEN1KMT2A
Maleic Anhydride SCHEMBL5638360 0.81 ALOX15 (0.39) ACHEHPGDMEN1KMT2AALDH1A1
Biphenyl SCHEMBL1930656 0.79 ALDH1A1 (0.50) LMNAHPGDKMT2AALDH1A1KDM4E
O-Xylene SCHEMBL28130786 0.78 TSHR (0.48) ACHETSHRHPGDMEN1KMT2A
Maleic Anhydride SCHEMBL28234298 0.78 ALOX15 (0.38) HPGDMEN1KMT2AALDH1A1CYP2C9
Naphthalene SCHEMBL6925512 0.76 CYP2A6 (0.47) LMNAALOX12HPGDALDH1A1CYP2C9
Benzoquinone SCHEMBL11705460 0.76 ACHE (0.65) ACHELMNATSHRALOX12CES2
Maleic Anhydride SCHEMBL28117971 0.75 ALOX15 (0.37) HPGDALDH1A1CYP2C9ALOX15TDP1
Maleic Anhydride SCHEMBL20573805 0.74 CES2 (0.38) LMNATSHRCES2CES1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535781-A Pressure-bearing PVC-U pipeline for building rain drainage and preparation method thereof 临海伟星新型建材有限公司 2023-08-04 CN claimed
CN-115926624-A Corrosion-resistant intumescent water-based steel structure fireproof coating and preparation method and application thereof 黄山中邦孚而道涂料有限公司 2023-04-07 CN claimed
CN-103570949-A Styrene-maleic anhydride grafted polyethylene glycol and preparation method thereof UNIV SHENYANG TECHNOLOGY 2014-02-12 CN claimed
CN-1035476-C Synthesis for copolymer of alternant phenylethylene & butadiene diacid anhydride SHANGHAI RESEARCH INST OF PETR (CN) 1997-07-23 CN claimed
CN-1069035-A Synthesizing of copolymer of alternant phenylethylene ﹠ butadiene diacid anhydride SHANGHAI RESEARCH INST OF PETR (CN) 1993-02-17 CN claimed
CN-115636964-B Preparation method of anti-tearing RPET film material for furniture surface coating 浙江盛康源新材料有限公司 2023-11-07 CN disclosed
CN-116535781-A Pressure-bearing PVC-U pipeline for building rain drainage and preparation method thereof 临海伟星新型建材有限公司 2023-08-04 CN disclosed
CN-116535781-A Pressure-bearing PVC-U pipeline for building rain drainage and preparation method thereof 临海伟星新型建材有限公司 2023-08-04 CN disclosed
CN-112759716-B High-molecular fluorescent material, preparation method thereof and fluorescent product thereof 中国石油化工股份有限公司 2023-04-11 CN disclosed
CN-115926624-A Corrosion-resistant intumescent water-based steel structure fireproof coating and preparation method and application thereof 黄山中邦孚而道涂料有限公司 2023-04-07 CN disclosed
CN-115636964-A Preparation method of anti-tear RPET film for furniture surface coating 浙江盛康源新材料有限公司 2023-01-24 CN disclosed
CN-112940186-B Preparation method of polyolefin solid-phase grafted maleic anhydride 中国科学院化学研究所 2022-11-22 CN disclosed
CN-1304969-A Adhesive ethylene copolymer resin composition and laminate using the same MITSUI CHEMICALS INC (JP) 2001-07-25 CN disclosed
CN-1297026-A Copolymer disperser and fuel contg. it, and lubricant composition contg. it and use thereof ETHYL CORP (US) 2001-05-30 CN disclosed
CN-1065544-C Copolymer dispersants from terminal vinyl propylene polymers ETHYL CORP (US) 2001-05-09 CN disclosed
WO-2001002442-A1 POLYSACCHARIDE ASPARTATE AVENTIS RES & TECH GMBH & CO (DE) 2001-01-11 WO disclosed
EP-1065217-A1 Polysaccharide aspartate Aventis Research & Technologies GmbH & Co. KG (DE) 2001-01-03 EP disclosed
CN-1165830-A Copolymer dispersants from terminal vinyl propylene polymers ETHYL CORP (US) 1997-11-26 CN disclosed
CN-1165531-A Adhesive ethylene copolymer resin composition and laminate using the same MITSUI PETROCHEMICAL IND (JP) 1997-11-19 CN disclosed
US-5032481-A Blend of polyester and polycarbonate EASTMAN KODAK COMPANY (US) 1991-07-16 US disclosed