Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.41 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.36 |
| ▸ | XDH | P47989 | 9/20 | 0.34 |
| ▸ | AHCY | P23526 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2558880 | 0.82 | PI4KA (0.44) | — | |
| SCHEMBL4426345 | 0.81 | XDH (0.54) | XDH | |
| SCHEMBL27983442 | 0.79 | CDK1 (0.59) | CDK1CCNB1CCNE1CDK2AHCY | |
| SCHEMBL28788637 | 0.77 | CDK1 (0.43) | CDK1CCNB1CCNE1CDK2XDH | |
| SCHEMBL1825531 | 0.76 | XDH (0.51) | CDK1CCNB1CCNE1CDK2XDH | |
| SCHEMBL15789757 | 0.73 | CDK1 (0.50) | CDK1CCNB1CCNE1CDK2 | |
| SCHEMBL7197886 | 0.70 | CDK1 (0.41) | CDK1CCNB1CCNE1CDK2AHCY | |
| SCHEMBL6013684 | 0.70 | CDK1 (0.54) | CDK1CCNB1CCNE1CDK2AHCY | |
| SCHEMBL28426470 | 0.70 | CRBN (0.58) | CRBN | |
| SCHEMBL6911224 | 0.69 | ADORA2A (0.41) | AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103243120-A | Method for adjusting and controlling gene expression level of cytochrome P450 (CYP) and application thereof | UNIV BEIJING | 2013-08-14 | — | — | CN | disclosed |
| CN-102719434-A | Specific modification for inhibiting RNA interference off-target effect | BIOMICS BIOTECHNOLOGIES CO LTD | 2012-10-10 | — | — | CN | disclosed |