Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.40 |
| ▸ | ST6GAL1 | P15907 | 5/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLA1 | P09884 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7166943 | 0.90 | NT5E (0.38) | NT5EST6GAL1LMNATHRBMTOR | |
| SCHEMBL7165495 | 0.88 | ST6GAL1 (0.37) | NT5EST6GAL1LMNATHRBMTOR | |
| SCHEMBL7165048 | 0.87 | ALDH1A1 (0.36) | NT5EALDH1A1POLBMEN1USP2 | |
| SCHEMBL7162782 | 0.83 | NT5E (0.47) | NT5EPOLBMEN1USP2KMT2A | |
| SCHEMBL7158886 | 0.83 | ST6GAL1 (0.40) | NT5EST6GAL1LMNATHRBMTOR | |
| SCHEMBL16131588 | 0.81 | ST6GAL1 (0.40) | NT5EST6GAL1LMNATHRBMTOR | |
| SCHEMBL7035981 | 0.81 | NT5E (0.36) | NT5EST6GAL1LMNATHRBMTOR | |
| SCHEMBL7037107 | 0.79 | NT5E (0.44) | NT5EALDH1A1POLBMEN1USP2 | |
| SCHEMBL7162036 | 0.79 | MEN1 (0.38) | NT5ELMNAALDH1A1POLBMEN1 | |
| SCHEMBL7162040 | 0.79 | RNASE1 (0.47) | NT5ELMNAALDH1A1POLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747389-B1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-RE38090-E1 | Antitumor activity; useful for treatment and prevention of cancers | Matsuda, Akira (JP) | 2003-04-22 | — | — | US | disclosed |
| US-5763418-A | NUCLEOTIDE ANTITUMOR AGENTS | Matsuda, Akira (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0747389-A1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |