Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DCK | P27707 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GAPDH | P04406 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | POLG | P54098 | 1/20 | 0.32 |
| ▸ | HRAS | P01112 | 1/20 | 0.31 |
| ▸ | PPM1B | O75688 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7157425 | 0.87 | NT5E (0.40) | ALDH1A1HTTPOLBMEN1USP2 | |
| SCHEMBL7162036 | 0.85 | MEN1 (0.38) | ALDH1A1HTTPOLBMEN1USP2 | |
| SCHEMBL16131607 | 0.82 | ALDH1A1 (0.38) | ALDH1A1DCKHTTBACE1ALB | |
| SCHEMBL13708357 | 0.81 | ALDH1A1 (0.37) | ALDH1A1DCKHTTBACE1ALB | |
| SCHEMBL7162782 | 0.80 | NT5E (0.47) | POLBMEN1USP2KMT2ANT5E | |
| SCHEMBL7162040 | 0.79 | RNASE1 (0.47) | ALDH1A1HTTALBPOLBMEN1 | |
| SCHEMBL7166943 | 0.78 | NT5E (0.38) | ALDH1A1HTTPOLBMEN1USP2 | |
| SCHEMBL13708355 | 0.77 | ALDH1A1 (0.42) | ALDH1A1DCKHTTBACE1ALB | |
| SCHEMBL7165495 | 0.76 | ST6GAL1 (0.37) | ALDH1A1HTTPOLBMEN1USP2 | |
| SCHEMBL11598911 | 0.76 | MEN1 (0.55) | ALDH1A1DCKHTTALBPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747389-B1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2003-09-10 | — | — | EP | disclosed |
| US-RE38090-E1 | Antitumor activity; useful for treatment and prevention of cancers | Matsuda, Akira (JP) | 2003-04-22 | — | — | US | disclosed |
| US-5763418-A | NUCLEOTIDE ANTITUMOR AGENTS | Matsuda, Akira (JP) | 1998-06-09 | — | — | US | disclosed |
| EP-0747389-A1 | 3'-SUBSTITUTED NUCLEOSIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |