SCHEMBL715824

SCHEMBL715824

Cc1cc(C)c(-c2c[c]c3c(c2)-c2cc(-c4c(C)cc(C)cc4C)ccc2C3)c(C)c1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL714161 0.73 METAP1 (0.43) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL7939919 0.72 MAPT (0.39) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL27862652 0.71 MEN1 (0.35) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL716718 0.70 MEN1 (0.31) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2340285 0.69 GRIA1 (0.50) ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2046255 0.65 CYP1A2 (0.39) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2052784 0.64 METAP1 (0.37)
SCHEMBL2051734 0.64 CYP1A2 (0.38) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL715825 0.63 ALDH1A1 (0.33) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL2047399 0.63 CHEK2 (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8357765-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-01-22 US disclosed
US-8288490-B2 Process for producing catalyst component for addition polymerization SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-16 US disclosed
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed
US-20120053311-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-03-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120053306-A1 PROCESS FOR PRODUCING CATALYST COMPONENT FOR ADDITION POLYMERIZATION PPOX, SOD1, AP1M1 MEN1 2714/4885ALDH1A1 1442/4885MAPT 467/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.