Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6224556 | 1.00 | MEN1 (0.43) | MEN1KMT2AKDM4EPARP1PTGS1 | |
| SCHEMBL6227910 | 1.00 | MEN1 (0.43) | MEN1KMT2AKDM4EPARP1PTGS1 | |
| SCHEMBL7323029 | 0.82 | TP53 (0.50) | MEN1KMT2AKDM4EPARP1PTGS1 | |
| SCHEMBL7416834 | 0.79 | SLC2A1 (0.48) | MEN1KMT2AKDM4EPARP1PTGS1 | |
| SCHEMBL9869279 | 0.79 | KIF11 (0.47) | MEN1KMT2AKDM4EPTGS1PTGS2 | |
| SCHEMBL7618084 | 0.78 | HTT (0.53) | MEN1KMT2AKDM4ESLC2A1TNKS2 | |
| SCHEMBL10481523 | 0.75 | KDM4E (0.52) | MEN1KMT2AKDM4EPARP1PTGS1 | |
| SCHEMBL7159367 | 0.73 | PTGS1 (0.46) | MEN1KMT2AKDM4EPARP1PTGS1 | |
| SCHEMBL6225217 | 0.73 | LMNA (0.51) | MEN1KMT2AKDM4EPARP1PTGS1 | |
| SCHEMBL11401420 | 0.72 | GPR84 (0.45) | KDM4EDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1446120-A4 | STEREOSPECIFIC ENRICHMENT OF HETEROCYCLIC ENANTIOMERS | R T ALAMO VENTURES I LLC (US) | 2005-01-26 | — | — | EP | disclosed |
| EP-1446120-A1 | STEREOSPECIFIC ENRICHMENT OF HETEROCYCLIC ENANTIOMERS | R.T. Alamo Ventures I, LLC (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003035071-A1 | STEREOSPECIFIC ENRICHMENT OF HETEROCYCLIC ENANTIOMERS | R.T. ALAMO VENTURES I, LLC (US) | 2003-05-01 | — | — | WO | disclosed |