Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 4/20 | 0.63 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | THPO | P40225 | 1/20 | 0.61 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.60 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.60 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5685741 | 0.99 | ADORA2A (0.61) | ADORA2AADORA2BTSHRPMP22SMN1; SMN2 | |
| SCHEMBL6636036 | 0.86 | ADORA2A (0.52) | ADORA2AADORA2BADORA3ADORA1 | |
| SCHEMBL1298953 | 0.84 | ADORA3 (0.74) | ADORA2AADORA2BTSHRPMP22SMN1; SMN2 | |
| SCHEMBL9495200 | 0.82 | ADORA2A (0.73) | ADORA2AADORA2BTSHRPMP22SMN1; SMN2 | |
| SCHEMBL7744261 | 0.82 | AHCY (0.46) | ADORA2AADORA2B | |
| SCHEMBL29877256 | 0.81 | AHCY (0.61) | ADORA2AADORA2BTSHRCYP2C19ADORA3 | |
| SCHEMBL177772 | 0.81 | AHCY (0.61) | ADORA2AADORA2BTSHRCYP2C19ADORA3 | |
| SCHEMBL28901883 | 0.81 | AHCY (0.61) | ADORA2AADORA2BTSHRCYP2C19ADORA3 | |
| SCHEMBL1320875 | 0.81 | ADORA3 (0.64) | TSHRPMP22TDP1ADORA3SLC29A1 | |
| SCHEMBL10579997 | 0.80 | ADORA2A (0.67) | ADORA2AADORA2BTSHRPMP22SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6586413-B2 | Methods and compositions for reducing ischemic injury of the heart by administering adenosine receptor agonists and antagonists | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES | 2003-07-01 | — | — | US | disclosed |
| US-6329349-B1 | CARDIOVASCULAR DISORDERS USING CARDIOPROTECTIVE AGENTS | TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA | 2001-12-11 | — | — | US | disclosed |