Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 4/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.46 |
| ▸ | PRMT5 | O14744 | 4/20 | 0.45 |
| ▸ | WDR77 | Q9BQA1 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177772 | 0.89 | AHCY (0.61) | AHCYADORA2AADORA2B | |
| SCHEMBL29877256 | 0.89 | AHCY (0.61) | AHCYADORA2AADORA2B | |
| SCHEMBL28901883 | 0.89 | AHCY (0.61) | AHCYADORA2AADORA2B | |
| SCHEMBL7744279 | 0.88 | AHCY (0.47) | AHCYADORA2AADORA2BPRMT5WDR77 | |
| SCHEMBL6636036 | 0.87 | ADORA2A (0.52) | ADORA2AADORA2BPRMT5WDR77 | |
| SCHEMBL5685741 | 0.83 | ADORA2A (0.61) | ADORA2AADORA2B | |
| SCHEMBL27741978 | 0.82 | AHCY (0.50) | AHCYADORA2AADORA2BPRMT5WDR77 | |
| SCHEMBL7161647 | 0.82 | ADORA2A (0.63) | ADORA2AADORA2B | |
| SCHEMBL1320875 | 0.81 | ADORA3 (0.64) | — | |
| SCHEMBL10365540 | 0.81 | PRMT5 (0.58) | AHCYADORA2AADORA2BPRMT5WDR77 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708781-B1 | A 3 ADENOSINE RECEPTOR AGONISTS | USA (US) | 2001-10-04 | — | — | EP | disclosed |
| US-5773423-A | XANTHINE RIBOSIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-30 | — | — | US | disclosed |
| WO-1995002604-A1 | A3 ADENOSINE RECEPTOR AGONISTS | THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1995-01-26 | — | — | WO | disclosed |