SCHEMBL7162154

SCHEMBL7162154

C=CCN(C(=O)O)c1ccccc1O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.41
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
MEN1 O00255 2/20 0.39
KDM4E B2RXH2 1/20 0.39
ESR1 P03372 1/20 0.38
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
NFKB1 P19838 1/20 0.37
CA4 P22748 1/20 0.37
ALDH1A1 P00352 5/20 0.36
AKR1B1 P15121 1/20 0.36
CYP1A2 P05177 1/20 0.36
POLB P06746 2/20 0.36
C5AR1 P21730 1/20 0.36
LMNA P02545 1/20 0.35
HPGD P15428 1/20 0.35
ALOX12 P18054 1/20 0.35
CCR6 P51684 1/20 0.35
CYP2C19 P33261 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11498178 0.81 TRPM8 (0.53) TSHRKMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL9274584 0.80 TSHR (0.40) TSHRKMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL11663103 0.79 ALDH1A1 (0.49) TSHRKMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL10797117 0.79 CA12 (0.41) TSHRKMT2ASMN1; SMN2MEN1CA1
SCHEMBL946547 0.78 TSHR (0.53) TSHRKMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL9329272 0.78 TSHR (0.44) TSHRKMT2ASMN1; SMN2MEN1ALDH1A1
SCHEMBL11482405 0.78 TSHR (0.41) TSHRKMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL5881190 0.77 TSHR (0.50) TSHRKMT2ASMN1; SMN2MEN1KDM4E
SCHEMBL1926093 0.77 TSHR (0.51) TSHRSMN1; SMN2ALDH1A1POLB
SCHEMBL9543595 0.76 KDM4E (0.50) TSHRKMT2AMEN1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003082233-A1 ALLYL-PHENOL COMPOUNDS IN ANDROGENIC DISORDERS GHISALBERTI CARLO (BR) 2003-10-09 WO disclosed