Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 6/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.38 |
| ▸ | POLA1 | P09884 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.37 |
| ▸ | PNP | P00491 | 1/20 | 0.37 |
| ▸ | PDE5A | O76074 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 3/20 | 0.35 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2732874 | 0.79 | XDH (0.52) | XDHHTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL7809886 | 0.78 | XDH (0.57) | XDHHTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL9059986 | 0.73 | XDH (0.55) | XDHHTTNCOA1SMN1; SMN2NCOA3 | |
| SCHEMBL3222570 | 0.68 | USP2 (0.44) | XDHHTTPOLA1GDAPDE5A | |
| SCHEMBL716337 | 0.67 | PI4KA (0.32) | — | |
| SCHEMBL29450710 | 0.67 | XDH (0.44) | XDHPOLA1GDAPNPPDE5A | |
| SCHEMBL473739 | 0.67 | PDE5A (0.47) | XDHPOLA1GDAPNPPDE5A | |
| SCHEMBL5133747 | 0.65 | PDE5A (0.51) | XDHPOLA1GDAPNPPDE5A | |
| SCHEMBL7680703 | 0.65 | XDH (0.60) | XDHPOLA1GDAPNPPDE5A | |
| SCHEMBL2435286 | 0.65 | GDA (0.57) | XDHGDAPNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8124609-B2 | Acyclic nucleoside derivatives | MEDIVIR AB (SE) | 2012-02-28 | — | — | US | disclosed |