Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A2 | P31639 | 3/20 | 0.39 |
| ▸ | PRCP | P42785 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | DRD1 | P21728 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622856 | 0.87 | SLC5A2 (0.40) | SLC5A2SLC6A2SLC6A4NAMPTSLC5A1 | |
| SCHEMBL27508666 | 0.86 | SLC5A2 (0.38) | SLC5A2PRCPNAMPTSLC5A1 | |
| SCHEMBL4837968 | 0.78 | PRCP (0.46) | PRCPSLC6A2SLC6A4ADRA2BADRA2C | |
| SCHEMBL4620798 | 0.75 | SLC5A2 (0.35) | SLC5A2SLC6A2SLC6A4HTR2AHTR2B | |
| SCHEMBL4622359 | 0.75 | LOXL2 (0.46) | SLC5A2SLC6A2SLC6A4ADRA2AADRA2B | |
| SCHEMBL9682302 | 0.74 | ADRA2A (0.40) | SLC5A2SLC6A2SLC6A4HTR1AADRA2A | |
| SCHEMBL17193852 | 0.74 | ADRA2A (0.40) | SLC5A2SLC6A2SLC6A4HTR1AADRA2A | |
| SCHEMBL9683908 | 0.74 | LMNA (0.40) | SLC6A2SLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL17193848 | 0.74 | LMNA (0.40) | SLC6A2SLC6A4ADRA2AADRA2BADRA2C | |
| SCHEMBL17193849 | 0.74 | LMNA (0.40) | SLC6A2SLC6A4ADRA2AADRA2BADRA2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114692-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2003-06-19 | — | — | US | disclosed |
| US-20030083508-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2003-05-01 | — | — | US | disclosed |
| EP-1259500-A1 | METHOD FOR THE PREPARATION OF CITALOPRAM | H. Lundbeck A/S (DK) | 2002-11-27 | — | — | EP | disclosed |
| US-20020004604-A1 | Method for the preparation of citalopram | H. LUNDBECK A/S (DK) | 2002-01-10 | — | — | US | disclosed |
| WO-2001062754-A1 | METHOD FOR THE PREPARATION OF CITALOPRAM | H. LUNDBECK A/S (DK) | 2001-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083508-A1 | Method for the preparation of citalopram | MAOB, MAOA, TPH1 | SLC5A2 195/4885PRCP 675/4885SLC6A2 5/4885 |
| US-20020004604-A1 | Method for the preparation of citalopram | MAOB, MAOA, TPH1 | SLC5A2 195/4885PRCP 675/4885SLC6A2 5/4885 |
| US-20030114692-A1 | Method for the preparation of citalopram | MAOB, MAOA, TPH1 | SLC5A2 195/4885PRCP 675/4885SLC6A2 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.