Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.48 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.38 |
| ▸ | IGF1R | P08069 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7164121 | 0.76 | KMT2A (0.39) | ALDH1A1ALOX15MAPTPOLBLMNA | |
| SCHEMBL5955129 | 0.74 | PLCG1 (0.55) | MGLLPLCG1ALDH1A1ALOX15USP2 | |
| SCHEMBL17281692 | 0.71 | MGLL (0.65) | MGLLPLCG1ALDH1A1ALOX15USP2 | |
| SCHEMBL7163494 | 0.70 | NOX4 (0.45) | ALDH1A1MAPTPOLBGAAMEN1 | |
| SCHEMBL5301085 | 0.70 | MGLL (0.54) | MGLLPLCG1ALDH1A1ALOX15USP2 | |
| SCHEMBL7164266 | 0.69 | FAAH (0.49) | MGLLALDH1A1ALOX15MAPTFAAH | |
| SCHEMBL5955006 | 0.67 | MGLL (0.50) | MGLLPLCG1ALDH1A1ALOX15USP2 | |
| SCHEMBL5293066 | 0.66 | MGLL (0.57) | MGLLPLCG1ALDH1A1ALOX15USP2 | |
| SCHEMBL7162436 | 0.66 | MAPT (0.37) | ALDH1A1MAPTLMNAGAANPSR1 | |
| SCHEMBL5954387 | 0.66 | MGLL (0.49) | MGLLPLCG1ALDH1A1ALOX15MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562814-B2 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | WYETH | 2003-05-13 | — | — | US | claimed |
| US-20020061883-A1 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | AMERICAN HOME PRODUCTS CORPORATION | 2002-05-23 | — | — | US | claimed |
| WO-2002028845-A1 | 3-THIOXO-[1,2,4]-OXADIAZINAN-5-ONE AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | WYETH (US) | 2002-04-11 | — | — | WO | claimed |
| US-6562814-B2 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | WYETH | 2003-05-13 | — | — | US | disclosed |
| US-20020061883-A1 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | AMERICAN HOME PRODUCTS CORPORATION | 2002-05-23 | — | — | US | disclosed |
| WO-2002028845-A1 | 3-THIOXO-[1,2,4]-OXADIAZINAN-5-ONE AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | WYETH (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061883-A1 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | AHR, PAOX, PPARA | MGLL 1703/4885PLCG1 581/4885ALDH1A1 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.